A wide variety of imaging approaches have been developed in the past few decades for
monitoring tumor oxygenation and hypoxia in vivo. In particular, nuclear medicine has seen …

Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …

Purpose: The Cancer Imaging Program of the National Cancer Institute convened a
workshop to assess the current status of hypoxia imaging, to assess what is known about the …

Tumor hypoxia presents a unique therapeutic challenge in the treatment of solid
malignancies. Not only does the presence of hypoxia compromise the efficacy of locally …

PURPOSE: Tumor hypoxia plays a fundamental role in tumor progression and treatment
resistance. Recent evidence that hypoxia also influences the regulation and transcription of …

Tumor regions that are transiently or chronically undersupplied with oxygen (hypoxia) and
nutrients, and enriched with acidic waste products, are common due to an abnormal and …

For many years, it has been known that hypoxia affects the response to radiotherapy in
human cancers. Hypoxic regions can develop as a tumor grows beyond the ability of its …

Hypoxia has been observed in a variety of human tumor types and evaluating tumor hypoxia
is important because it increases resistance to radiotherapy and chemotherapy by inducing …

Hypoxia, a prevalent characteristic of most solid malignant tumors, contributes to diminished
therapeutic responses and more aggressive phenotypes. The term hypoxia has two …

Purpose Hypoxia is a condition of insufficient oxygen to support metabolism which occurs
when the vascular supply is interrupted, or when a tumour outgrows its vascular supply. It is …