The effects of monosodium glutamate on PSMA radiotracer uptake in men with recurrent prostate cancer: a prospective, randomized, double-blind, placebo-controlled …

S Harsini, H Saprunoff, T Alden… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA) is an excellent target for theranostic
applications in prostate cancer. However, PSMA-targeted radioligand therapy can cause …

The impact of monosodium glutamate on 68Ga-PSMA-11 biodistribution in men with prostate cancer: A prospective randomized, controlled imaging study

WR Armstrong, A Gafita, S Zhu, P Thin… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA) has been targeted for PET imaging and
radioligand therapy (RLT) in patients with prostate cancer. Xerostomia is a common side …

Monosodium glutamate reduces 68Ga-PSMA-11 uptake in salivary glands and kidneys in a preclinical prostate cancer model

E Rousseau, J Lau, HT Kuo, Z Zhang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
We evaluated the ability of monosodium glutamate (MSG) to reduce salivary and kidney
uptake of a prostate-specific membrane antigen (PSMA) radioligand without affecting tumor …

[HTML][HTML] The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research

EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …

PMPA for nephroprotection in PSMA-targeted radionuclide therapy of prostate cancer

C Kratochwil, FL Giesel, K Leotta, M Eder… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Radioactive ligands for the prostate-specific membrane antigen (PSMA) are under
development for therapy of metastasized prostate cancer. Since PSMA expression is also …

[HTML][HTML] Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy

EAM Ruigrok, N van Vliet, SU Dalm, E de Blois… - European journal of …, 2021 - Springer
Purpose Various radiolabeled prostate-specific membrane antigen (PSMA)–targeting
tracers are clinically applied for prostate cancer (PCa) imaging and targeted radionuclide …

Comparison of prostate-specific membrane antigen expression levels in human salivary glands to non-human primates and rodents

J Roy, BM Warner, F Basuli, X Zhang… - Cancer biotherapy & …, 2020 - liebertpub.com
Background: Prostate-specific membrane antigen (PSMA) has emerged as a promising
target for developing radionuclide therapy (RNT) in prostate cancer; however, accumulation …

Reduction of 68Ga-PSMA renal uptake with mannitol infusion: preliminary results

F Matteucci, E Mezzenga, P Caroli, V Di Iorio… - European journal of …, 2017 - Springer
Purpose Urea-based prostate-specific membrane antigen (PSMA) ligands labelled with 68
Ga or 177 Lu are new tracers with great potential for theranostic approaches in prostate …

Assessment of an 18F-labeled phosphoramidate peptidomimetic as a new prostate-specific membrane antigen–targeted imaging agent for prostate cancer

SE Lapi, H Wahnishe, D Pham, LY Wu… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found
on the surface of late-stage and metastatic prostate cancer and a well-known imaging …

[HTML][HTML] Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent

KLS Chatalic, S Heskamp, M Konijnenberg… - Theranostics, 2016 - ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) is a well-established target for nuclear imaging
and therapy of prostate cancer (PCa). Radiolabeled small-molecule PSMA inhibitors are …