68Ga-Pentixafor PET/CT for detection of chemokine receptor CXCR4 expression in myeloproliferative neoplasms

S Kraus, A Dierks, L Rasche, O Kertels… - Journal of Nuclear …, 2022 - Soc Nuclear Med
CXC motif chemokine receptor 4 (CXCR4) is an attractive target for cancer diagnosis and
treatment, as it is overexpressed in many solid and hematologic malignancies. This study …

Imaging of CXC motif chemokine receptor 4 expression in 690 patients with solid or hematologic neoplasms using 68Ga-pentixafor PET

AK Buck, A Haug, N Dreher, A Lambertini… - Journal of Nuclear …, 2022 - Soc Nuclear Med
In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …

[HTML][HTML] Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

R Lewis, S Habringer, M Kircher, M Hefter, CA Peuker… - EJNMMI research, 2021 - Springer
Background The chemokine receptor CXCR4 is frequently overexpressed and associated
with adverse prognosis in most hematopoietic malignancies and solid cancers. Recently …

[HTML][HTML] [68Ga] Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma-Comparison to [18F] FDG and laboratory values

C Lapa, M Schreder, A Schirbel, S Samnick… - Theranostics, 2017 - ncbi.nlm.nih.gov
Abstract Chemokine (CXC motif) receptor 4 (CXCR4) is a key factor for tumor growth and
metastasis in several types of human cancer including multiple myeloma (MM). Proof-of …

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

K Philipp‐Abbrederis, K Herrmann, S Knop… - EMBO molecular …, 2015 - embopress.org
CXCR 4 is a G‐protein‐coupled receptor that mediates recruitment of blood cells toward its
ligand SDF‐1. In cancer, high CXCR 4 expression is frequently associated with tumor …

[HTML][HTML] CXCR4-directed PET/CT with [68 Ga]Ga-pentixafor in solid tumors—a comprehensive analysis of imaging findings and comparison with histopathology

N Dreher, S Hahner, CT Fuß, W Schlötelburg… - European Journal of …, 2023 - Springer
Background CXC motif chemokine receptor 4 (CXCR4) is overexpressed in various solid
cancers and can be targeted by CXCR4-directed molecular imaging. We aimed to …

68Ga-Pentixafor PET/CT Demonstrating In Vivo CXCR4 Receptor Overexpression in Rare Lung Malignancies: Correlation with Histologic and Histochemical Findings

A Watts, B Singh, H Singh, H Kaur, A Bal… - Journal of Nuclear …, 2022 - Soc Nuclear Med
68Ga-pentixafor PET/CT imaging allows noninvasive assessment of CXC chemokine
receptor type 4 (CXCR4) expression in various malignancies, but its use in rare lung cancer …

Molecular imaging of chemokine receptor CXCR4 in non–small cell lung cancer using 68Ga-pentixafor PET/CT: comparison with 18F-FDG

T Derlin, D Jonigk, J Bauersachs… - Clinical nuclear …, 2016 - journals.lww.com
We report the case of a 62-year-old woman with a history of ST-elevation myocardial
infarction who underwent 68 Ga-Pentixafor PET/CT for characterization of postinfarct …

Imaging CXCR4 receptors expression for staging multiple myeloma by using 68Ga-Pentixafor PET/CT: comparison with 18F-FDG PET/CT

AS Shekhawat, B Singh, P Malhotra… - The British Journal of …, 2022 - academic.oup.com
Objectives: 68Ga-Pentixafor positron emission tomography (PET) imaging targets CXCR4
expression which is overexpressed in multiple myeloma (MM). In this study, we evaluated …

[PDF][PDF] Interobserver agreement rates on CXC Motif chemokine receptor 4–directed molecular imaging and therapy

PE Hartrampf, A Kosmala, SE Serfling… - Clinical nuclear …, 2022 - journals.lww.com
Background We aimed to evaluate the interobserver agreement rates in patients scanned
with CXC motif chemokine receptor 4 (CXCR4)–directed PET/CT, including the rate of …