Multi-drug loaded exosomes for combined anti-tumor therapy and drug delivery monitoring via pre-targeting strategy

R Qian, X Lan, R An - 2021 - Soc Nuclear Med
1218 Objectives: Exosomes, a type of natural biomaterials with intrinsic tumor-homing
capacities, have recently been extensively explored as drug delivery systems. The aim of …

Multi-antitumor therapy and synchronous imaging monitoring based on exosome

R Qian, B Jing, D Jiang, Y Gai, Z Zhu, X Huang… - European journal of …, 2022 - Springer
Background Tumor-derived exosomes (TEX) have shown great potential for drug delivery
and tumor targeting. Here, we developed a novel multi-drug loaded exosomes nanoprobe …

[HTML][HTML] Hydrophobic insertion-based engineering of tumor cell-derived exosomes for SPECT/NIRF imaging of colon cancer

B Jing, Y Gai, R Qian, Z Liu, Z Zhu, Y Gao… - Journal of …, 2021 - Springer
Background Tumor cell-derived exosomes (TEx) have emerged as promising nanocarriers
for drug delivery. Noninvasive multimodality imaging for tracing the in vivo trafficking of TEx …

Multimodality PET/CT and NIRF imaging for image-guided surgery of colon cancer with exosomes based nanoprobe

B Jing, R Qian, Y Gai, X Lan, R An - 2019 - Soc Nuclear Med
662 Objectives: Exosomes, known as nano-sized extracellular vesicles, emerged as a
promising carrier for multimodality imaging due to their biological origin, non-toxic and …

[HTML][HTML] ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy

Z Wan, X Gan, R Mei, J Du, W Fan, M Wei… - Journal of …, 2022 - Springer
Background Exosomes are recognized as effective platforms for targeted delivery for their
high physicochemical stability and biocompatibility. However, most of the exosomes are …

Biocompatible exosomes nanodrug cargo for cancer cell bioimaging and drug delivery

A Qambrani, FU Rehman, T Tanziela… - Biomedical …, 2021 - iopscience.iop.org
Therapy against cancer remains a daunting issue for human health, despite remarkable
innovations in many areas of pathology. In situ biosynthesized nanoclusters bestow a novel …

[HTML][HTML] Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

High-throughput single-cell analysis of exosome mediated dual drug delivery, in vivo fate and synergistic tumor therapy

J Wang, G Li, C Tu, X Chen, B Yang, Y Huo, Y Li… - Nanoscale, 2020 - pubs.rsc.org
Exosomes could serve as delivery platforms, owing to their good biocompatibility, stability,
and long blood circulation time. Tracking the biological fate of exosomes in vivo is essential …

Application of exosomes as nanocarriers in cancer therapy

J Hu, J Zhu, J Chai, Y Zhao, J Luan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancers remained the most common lethal disease in the world. Although the treatment
choice to cancers are still limited, significant progress has been made over the past years …

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

H Gomari, M Forouzandeh Moghadam… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Exosomes are small 30–100 nm vesicles secreted by various cell types. They are
released by most cell types, indicating their important role in physiological and pathological …