Multi-drug loaded exosomes for combined anti-tumor therapy and drug delivery monitoring via pre-targeting strategy
R Qian, X Lan, R An - 2021 - Soc Nuclear Med
1218 Objectives: Exosomes, a type of natural biomaterials with intrinsic tumor-homing
capacities, have recently been extensively explored as drug delivery systems. The aim of …
capacities, have recently been extensively explored as drug delivery systems. The aim of …
Multi-antitumor therapy and synchronous imaging monitoring based on exosome
Background Tumor-derived exosomes (TEX) have shown great potential for drug delivery
and tumor targeting. Here, we developed a novel multi-drug loaded exosomes nanoprobe …
and tumor targeting. Here, we developed a novel multi-drug loaded exosomes nanoprobe …
[HTML][HTML] Hydrophobic insertion-based engineering of tumor cell-derived exosomes for SPECT/NIRF imaging of colon cancer
Background Tumor cell-derived exosomes (TEx) have emerged as promising nanocarriers
for drug delivery. Noninvasive multimodality imaging for tracing the in vivo trafficking of TEx …
for drug delivery. Noninvasive multimodality imaging for tracing the in vivo trafficking of TEx …
Multimodality PET/CT and NIRF imaging for image-guided surgery of colon cancer with exosomes based nanoprobe
662 Objectives: Exosomes, known as nano-sized extracellular vesicles, emerged as a
promising carrier for multimodality imaging due to their biological origin, non-toxic and …
promising carrier for multimodality imaging due to their biological origin, non-toxic and …
[HTML][HTML] ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy
Z Wan, X Gan, R Mei, J Du, W Fan, M Wei… - Journal of …, 2022 - Springer
Background Exosomes are recognized as effective platforms for targeted delivery for their
high physicochemical stability and biocompatibility. However, most of the exosomes are …
high physicochemical stability and biocompatibility. However, most of the exosomes are …
Biocompatible exosomes nanodrug cargo for cancer cell bioimaging and drug delivery
Therapy against cancer remains a daunting issue for human health, despite remarkable
innovations in many areas of pathology. In situ biosynthesized nanoclusters bestow a novel …
innovations in many areas of pathology. In situ biosynthesized nanoclusters bestow a novel …
[HTML][HTML] Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application
Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …
High-throughput single-cell analysis of exosome mediated dual drug delivery, in vivo fate and synergistic tumor therapy
Exosomes could serve as delivery platforms, owing to their good biocompatibility, stability,
and long blood circulation time. Tracking the biological fate of exosomes in vivo is essential …
and long blood circulation time. Tracking the biological fate of exosomes in vivo is essential …
Application of exosomes as nanocarriers in cancer therapy
J Hu, J Zhu, J Chai, Y Zhao, J Luan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancers remained the most common lethal disease in the world. Although the treatment
choice to cancers are still limited, significant progress has been made over the past years …
choice to cancers are still limited, significant progress has been made over the past years …
Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle
H Gomari, M Forouzandeh Moghadam… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Exosomes are small 30–100 nm vesicles secreted by various cell types. They are
released by most cell types, indicating their important role in physiological and pathological …
released by most cell types, indicating their important role in physiological and pathological …