[PDF][PDF] Biodistribution and dosimetry of technetium-99m-hydrazino nicotinamide IgG: comparison with indium-111-DTPA-IgG

RJ Callahan, SA Barrow, MJ Abrams… - Journal of Nuclear …, 1996 - Soc Nuclear Med
Methods: Initial biodistributionand dosimetry studies were per formed in six normal male
volunteers. Additionally,"" Tc-IgG and 1111n-DTPA-IgGwere co-injected into six subjects …

Technetium-99m labelled hydrazinonicotinamido human non-specific polyclonal immunoglobulin G for detection of infectious foci: a comparison with two other …

RAMJ Claessens, OC Boerman, EB Koenders… - European journal of …, 1996 - Springer
Recently a new linker—hydrazinonicotinate (HYNIC)—was introduced for labelling of
proteins and peptides with technetium-99m. HYNIC and other linkers have been used for …

[PDF][PDF] Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats

MJ Abrams, M Juweid, DA Schwartz… - Journal of Nuclear …, 1990 - Soc Nuclear Med
MATERIALSAND METHODS Radiopharmaceuticals: 111ln-Labeled IgG Human
polyclonalIgG (Gammimune, Cutter Laborato lies, Emeryville, CA) was radiolabeled with †…

[PDF][PDF] Technetium-99m labeled to human immunoglobulin G through the nicotinyl hydrazine derivative: a clinical study

ETM Dams, WJG Oyen, OC Boerman… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Study Design This prospective, comparative study was performed with 37 patients (22
women and 15men; mean age= 54 yr, range= 17-78 yr) who were referred to the department …

Retention of technetium-99m in infectious foci in rats after release from technetium-99m labelled human non-specific polyclonal immunoglobulin G: a dual-label study …

RAMJ Claessens, EB Koenders, WJG Oyen… - European journal of …, 1996 - Springer
In an effort to contribute to the understanding of the mechanism of uptake of technetium-99m
labelled non-specific polyclonal human immunoglobulin G (hIgG) in inflammatory lesions we …

Technetium-99m labeled monoclonal antibodies: evaluation of reducing agents

ML Thakur, J DeFulvio, MD Richard, CH Park - International journal of …, 1991 - Elsevier
We have evaluated five compounds, stannous chloride (SnCl 2), 2-mercaptoethanol (2-ME),
dithiothreitol (DTT), dithioerythritol (DTE), and ascorbic acid (AA) to reduce monoclonal …

Imaging of focal sites of inflammation in rhesus monkeys with 99mTc-labeled human polyclonal IgG

AJ Fischman, HF Solomon, JW Babich… - Nuclear medicine and …, 1994 - Elsevier
The biological behavior of human polyclonal immunoglobulin G (IgG) radiolabeled with 99m
Tc via a nicotinyl hydrazine derivative, was evaluated in Rhesus monkeys. 99m Tc-IgG and …

99m Tc human IgG radiolabelled by HYNIC. Biodistribution and scintigraphy of experimentally induced inflammatory lesions in animal model

U Karczmarczyk, A Markiewicz… - Nuclear Medicine …, 2004 - journals.viamedica.pl
BACKGROUND: Our goal was the efficient labelling of highly purified human
gammaglobulin. This radioactive protein fraction can be used as a basic compound of …

Species and immunoglobulin preparation related effects on the biodistribution of technetium-99m-labelled immunoglobulin G in a baboon model

WKA Louw, IC Dormehl, N Hugo… - European journal of …, 1993 - Springer
Technetium-99m-labelled immunoglobulin G (99m Tc-IgG) is a convenient and useful radio-
pharmaceutical for the scintigraphic detection of inflammatory foci. However, unfavourable …

[PDF][PDF] Directly and Indirectly Technetium-99m-Labeled Antibodies A—Comparison of In Vitro and Animal In Vivo Properties

DJ Hnatowich, G Mardirossian… - Journal of Nuclear …, 1993 - Soc Nuclear Med
MATERIALSAND METHODS This investigation was performed with B72. 3 and Cl 10in their
intact IgG form. The B72. 3 antibody, an IgGl, is directed against the antigen tag-72 which is …