DISCUSSION Other authors have obtained similar results. Newman (3) derived an
expression for tracer dilution in a model of central circulation with two mixing chambers …

The techniques of tracer dilution in the circulation, and of tracer uptake by and washout from
an organ, may be described using expressions that are general and are not dependent on …

We describe the theory of a technique for the noninvasive measurement of organ blood flow
which is based on the principle of fractionation of cardiac output and is applicable with any …

Based upon many distribution studies in our labo ratory (1, 2), we have found it much more
useful to express individual tissue concentrations as percent of mean body concentration …

We propose to model quantitation of physical quan tities as a parameter estimation problem
in which the parameters are the quantities of interest, such as the size, location, and activity …

Three-Hour Volume of Distribution Method: An Accurate Simplified Method of Glomerular
Filtration Rate Measurement Page 1 Technical Notes Three-Hour Volume of Distribution Method …

Data obtained from tracer studies often consist of serial measurements after administration
of radioisotope. Very little work has been published on how the error in the data affects the …

INVESTIGATIVENUCLEAR MEDICINE where C@(T) is the instantaneous local tissue
radiotracer concentration (cps/unit weight) after an infusion time of T seconds, derived from a …

RESULTS Phantom measurements. The method was tested with a phantom simulating lung
and chest wall. Boxes were used to imitate the chestwall; theywereconstructedof3 …

A formula has been derived for the calculation of renal clearance with the use of a single
plasma sample. The formula is based on a one‐compartment model. A small correction for …