Measurement of myocardial blood flow with PET using 1-11C-acetate

RR Sciacca, O Akinboboye, RL Chou… - Journal of Nuclear …, 2001 - Soc Nuclear Med
11C-acetate has been used extensively for the noninvasive assessment of myocardial
oxygen consumption and viability with PET. The use of early uptake of acetate by the heart …

Potential of [11C] acetate for measuring myocardial blood flow: Studies in normal subjects and patients with hypertrophic cardiomyopathy

SAJ Timmer, M Lubberink, T Germans… - Journal of nuclear …, 2010 - Elsevier
Background Measuring the rate of clearance of carbon-11 labelled acetate from myocardium
using positron emission tomography (PET) is an accepted technique for noninvasively …

Simple and accurate assessment of forward cardiac output by use of 1-11C-acetate PET verified in a pig model

J Sörensen, E Ståhle, B Långström… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Dynamic 1-11C-acetate PET (AC-PET) allows quantification of myocardial blood flow and
oxidative metabolism. We wanted to determine the accuracy of AC-PET in measuring …

[1-11C] Acetate as a quantitative perfusion tracer in myocardial PET

J van den Hoff, W Burchert, AR Börner… - Journal of Nuclear …, 2001 - Soc Nuclear Med
Our objective was to investigate the properties of [1-11C] acetate as a quantitative perfusion
tracer for myocardial PET studies. Methods: We determined the flow dependence of the …

Improved spillover correction model to quantify myocardial blood flow by 11C-acetate PET: comparison with 15OH2O PET

Y Mori, O Manabe, M Naya, Y Tomiyama… - Annals of nuclear …, 2015 - Springer
Objective 11 C-acetate has been applied for evaluation of myocardial oxidative metabolism
and can simultaneously estimate myocardial blood flow (MBF). We developed a new …

Assessment of myocardial blood flow using 15O-water and 1-11C-acetate in rats with small-animal PET

P Herrero, J Kim, TL Sharp, JA Engelbach… - Journal of Nuclear …, 2006 - Soc Nuclear Med
This feasibility study was undertaken to determine whether myocardial blood flow (MBF,
mL/g/min) could be quantified noninvasively in small rodents using microPET and 15O …

Compartment model for measuring myocardial oxygen consumption using (1-(11) C) acetate

KT Sun, K Chen, H Sung-Chen… - The Journal of Nuclear …, 1997 - search.proquest.com
Abstract Although [1-11C] acetate has been validated as a PET tracer for myocardial oxygen
consumption (MVO2) in animals and humans, mono-and biexponential fitting of the tissue …

Cardiac studies in rats with/sup 11/C-acetate and PET: a comparison with/sup 13/N-ammonia

M Bentourkia, E Croteau, R Langlois… - … on Nuclear Science, 2002 - ieeexplore.ieee.org
Regional myocardial blood flow (MBF) can be assessed noninvasively with dynamic
positron emission tomography (PET) and/sup 13/N-ammonia or/sup 11/C-acetate. The latter …

[PDF][PDF] A kinetic model for cardiac PET with [1-carbon-11]-acetate

J Van den Hoff, W Burchert, HG Wolpers… - Journal of Nuclear …, 1996 - Soc Nuclear Med
Conclusion: The kinetics of [1-11C]-acetate are adequately de scribed by a five-
compartment model. One-and two-compartment models are sufficient for simultaneous …

Reappraisal of a single-tissue compartment model for estimation of myocardial oxygen consumption by [11C] acetate PET: an alternative to conventional …

SAJ Timmer, M Lubberink… - Nuclear medicine …, 2011 - journals.lww.com
Background Myocardial washout kinetics of carbon-11 labelled acetate ([11 C] acetate) by
positron emission tomography (PET) closely correlate with myocardial oxygen consumption …