Differential distribution of dopamine D2 and D3 receptors in the Rhesus brain measured with PET
159 Objectives PET tracers for dopamine D 2-like receptors display little selectivity for D 2
and D 3 receptors. Consequently, the differential distribution of D 2 and D 3 receptors in …
and D 3 receptors. Consequently, the differential distribution of D 2 and D 3 receptors in …
Dopamine D1 Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates
O Barret, L Zhang, D Alagille… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Non–catechol-based high-affinity selective dopamine D1 receptor (D1R) agonists were
recently described, and candidate PET ligands were selected on the basis of favorable …
recently described, and candidate PET ligands were selected on the basis of favorable …
Synthesis and pre-clinical evaluation of a potential radiotracer for PET imaging of the dopamine D 3 receptor
MN Stewart, X Shao, TJ Desmond, TJ Forrest… - …, 2018 - pubs.rsc.org
There is considerable interest in using positron emission tomography (PET) imaging to
understand the function of dopamine D3 receptors. Due to high sequence homology with D2 …
understand the function of dopamine D3 receptors. Due to high sequence homology with D2 …
Development of PET Radiotracers for the Dopamine D3 Receptor
859 Objectives: Dysfunction of the dopaminergic system has been implicated in neurological
and psychiatric disorders such as Parkinson's disease, schizophrenia, depression and …
and psychiatric disorders such as Parkinson's disease, schizophrenia, depression and …
Rodent PET evaluation of fluorine-18 labeled dopamine D3 receptor agonist, 18F-7-OH-FHXPAT
D Majji, ML Pan, C Constantinescu, MR Mirbolooki… - 2012 - Soc Nuclear Med
1634 Objectives Dopamine D3 receptors have been associated with a number of
neurological and psychiatric disorders. Development of agonist-based imaging …
neurological and psychiatric disorders. Development of agonist-based imaging …
18F-MCL-524, an 18F-labeled dopamine D2 and D3 receptor agonist sensitive to dopamine: a preliminary PET study
SJ Finnema, V Stepanov, R Nakao… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET has been used to examine changes in neurotransmitter concentrations in the living
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …
[18F] MCL-524, an 18F-labeled dopamine D2/D3 receptors agonist radioligand with higher binding signal than [11C] MNPA
S Finnema, V Stepanov, R Nakao, A Sromek… - 2012 - Soc Nuclear Med
360 Objectives Dopamine D 2 and D 3 (D 2/D 3) receptors agonist PET radioligands have
recently been demonstrated to have improved sensitivity to endogenous dopamine level …
recently been demonstrated to have improved sensitivity to endogenous dopamine level …
Fluorine-18 labeled benzamide analogues as dopamine D3 receptor PET radiotracers
565 Objectives: Partial agonists or antagonists of D 3 ligands that can reduce the interaction
of psychostimulant-induced increases in synaptic dopamine levels with the D 3 receptor may …
of psychostimulant-induced increases in synaptic dopamine levels with the D 3 receptor may …
Biodistribution studies of two 18F-labeled pyridinylphenyl amides as subtype selective radioligands for the dopamine D3 receptor
C Hocke, P Cumming, S Maschauer, T Kuwert… - Nuclear Medicine and …, 2014 - Elsevier
Introduction Dopamine D3 receptors are implicated in various neuropsychiatric diseases,
drug abuse and alcoholism, but specific agents for D3 molecular imaging are lacking. We …
drug abuse and alcoholism, but specific agents for D3 molecular imaging are lacking. We …
Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride
Substituted benzamides such as 11C-raclopride or 123I-iodobenzamide are selective
radiotracers for PET and SPECT imaging of D2-like dopamine (DA) receptors. 18F …
radiotracers for PET and SPECT imaging of D2-like dopamine (DA) receptors. 18F …