[PDF][PDF] Differential skeletal uptake of Tc-99m-tagged pyrophosphate and methylene diphosphonate in leukemia

R Armas, R Neumann, SJ Goldsmith - Journal of nuclear …, 1983 - Soc Nuclear Med
Thus the failure of bone PPi uptake in these patients could be due to pyrophosphatase
hydrolysis of PPi in the circulation, which— given the ubiquitousness of pyrophosphatases …

Unusual bone scintigraphy in chronic myelogenous leukemia—report of a case showing extensive uptake defect

Y Ishino, C Nakayama, H Shiozaki, H Hidaka… - European journal of …, 1988 - Springer
An extensive 99m Tc-methylene diphosphonate uptake defect was observed on bone
scintigraphy in a 35-year-old male with chronic myelogenous leukemia. This type of bone …

[PDF][PDF] Kinetics of 99mTc-labeled pyrophosphate and polyphosphate in man

GT Krishnamurthy, RJ Huebotter… - Journal of Nuclear …, 1975 - Soc Nuclear Med
MATERIALS AND METHODS The procedure was identical with the methods used in our
previous studies (6, 7, 9). Ten patients with suspected bone lesions were chosen from a list …

[PDF][PDF] Skeletal uptake of pyrophosphate labeled with technetium-95m and technetium-96, as evaluated by autoradiography

A Guillemart, JC Besnard, A Le Pape… - Journal of Nuclear …, 1978 - Soc Nuclear Med
RESULTS Validity of the radlonudide. The decay schemes of Tc-95m and Tc-96 show that
there is no emission of beta particles; but there is an abundance of cx tranuclear electrons of …

What do we want from a bone-scanning agent?

I Fogelman, RG Bessent - Journal of Nuclear Medicine, 1980 - Soc Nuclear Med
Table I presentsour initial resultsfrom repeated24-hr whole bodyretentionstudies,
usingbothhydroxyethylidenediphospho nate (HEDP) and methylene diphosphonate (MDP) …

[PDF][PDF] Enhanced detection of a skeletal lesion with delayed 99mTc-polyphosphate bone scanning

WD Kaplan, BL Holman, PA Liebow… - Journal of Nuclear …, 1974 - Soc Nuclear Med
DISCUSSION Blood clearance studies in humans indicate that within 30— 60 mm,
between 45 and 50% of the 99mTc.. polyphosphate is associated with bone; the remaining …

A comparison of phosphate bone-scanning agents in normal subjects and patients with malignant disease

DL Citrin, RG Bessent, JB Tuohy… - The British Journal of …, 1975 - birpublications.org
None of the established bone-scanning compounds 85Sr, 87Srm nor 18F is entirely
satisfactory and because of this the place of skeletal scanning is not clearly defined. 18F is …

[PDF][PDF] Increased localization of 99mTc-pyrophosphate in a bone island: case report

EA Sickles, HK Genant, PB Hoffer - Journal of Nuclear Medicine, 1976 - Soc Nuclear Med
DISCUSSION The skeletal uptake of technetium-tagged phos phorus compounds (13— 15)
is thought to be due pri manly to increased regional blood flow (16). Thus, the usual …

[CITATION][C] Quantification of skeletal Tc-99m labeled phosphates to detect metabolic bone disease

RA Holmes - Journal of Nuclear Medicine, 1978 - Soc Nuclear Med
As a highly sensitive indicator of disturbed bone metabolism, the Tc-99m-labeled
phosphates have dramatically established their role in the clinical assessment of bone …

[PDF][PDF] Splenic accumulation of technetium-99m-methylene diphosphonate in a transfusion-dependent patient with chronic myelogenous leukemia

D Franceschi, JS Nagel, BL Holman - Journal of Nuclear Medicine, 1990 - Soc Nuclear Med
DISCUSSION Although accumulation of bone-seeking radiophar maceuticals in the spleen
is an exceptional phenome non, it is well-known and documented in patients with sickle cell …