Arachidonic acid (AA) is found in high concentrations in brain phospholipids and is released
as a second messenger during neurotransmission and much more so during …

Dysreglulated brain arachidonic acid (AA) metabolism is involved in chronic inflammation
and is influenced by apolipoprotein E4 (APOE4) genotype, the strongest genetic risk factor …

The in viro behavior of 20-[" Ffluoroarachidonic acid (" F-FAA) was investigated to evaluate
its potential use as a radiotracer for studying the regional brain and heart lipid metabolism …

Glia account for 90% of human brain cells and have a significant role in brain homeostasis.
Thus, specific in vivo imaging markers of glial metabolism are potentially valuable. In the …

Imaging of the glial activation that occurs in response to central nervous system trauma and
inflammation could become a powerful technique for the assessment of several …

Incorporation coefficients (K*) of arachidonic acid (AA) in the brain are increased in a rat
model of neuroinflammation, as are other markers of AA metabolism. Data also indicate that …

1033 Objectives Neuroinflammation plays an important role in many neurodegenerative
diseases, including amyotrophic lateral sclerosis, Parkinson's disease, multiple sclerosis …

Introduction Fatty acid amide hydrolase (FAAH) has a significant role in regulating
endocannabinoid signaling in the central nervous system. As such, FAAH inhibitors are …

INTRODUCTION: Changes in glial metabolism in brain ischemia, Alzheimer's disease,
depression, schizophrenia, epilepsy and manganese neurotoxicity have been reported in …

Arachidonic acid (AA) is involved in signal transduction, neuroinflammation, and production
of eicosanoid metabolites. The AA brain incorporation coefficient (K*) is quantifiable in vivo …