A pilot study on the pharmacokinetics, biodistribution and radiation dose of 99mTc-RGD-BBN in healthy volunteers

Q Ma, S Gao, T Ji, B Chen, B Ji - 2014 - Soc Nuclear Med
181 Objectives 99m Tc-RGD-BBN is a new SPECT radiotracer for several tumor imaging
with high uptake where integrin αvβ3 or gastrin releasing peptide receptor (GRPR) is highly …

Pharmacokinetics and radiation dosimetry of {sup 99m} Tc-3PRGD {sub 2} in healthy individuals: A pilot study

C Guanghui, G Shi, JI Tiefeng, MA Qingjie… - Nuclear Science and …, 2012 - osti.gov
{sup 99m} Tc-3PRGD {sub 2} is a new SPECT radiotracer for several tumor imaging with
high uptake where integrin α {sub v} β {sub 3} is highly expressed. This pilot study was to …

[HTML][HTML] An Exploratory Study on 99mTc-RGD-BBN Peptide Scintimammography in the Assessment of Breast Malignant Lesions Compared to 99mTc-3P4-RGD2

Q Chen, Q Ma, M Chen, B Chen, Q Wen, B Jia… - PLoS …, 2015 - journals.plos.org
Purpose This study aimed to explore the diagnostic performance of single photon emission
computed tomography/computerized tomography (SPECT/CT) using a new radiotracer …

The comparison of Tc-99m-BPHA with Tc-99m-DTPA on the pharmacokinetics and evaluation of renal function

RF Wang, XK He, CL Zhang, L Huo, ZL Fu… - World Journal of …, 2002 - inis.iaea.org
[en] Aim: It has been confirmed that radionuclide non-invasive renal dynamic imaging plays
an important role in evaluating the renal function, but Tc-99m-DTPA that is widely used in …

Biodistribution and dosimetry of 99mTc-RP527, a gastrin-releasing peptide (GRP) agonist for the visualization of GRP receptor–expressing malignancies

C Van de Wiele, F Dumont, RA Dierckx… - Journal of Nuclear …, 2001 - Soc Nuclear Med
The aim of this study was to determine the human biodistribution and radiation dosimetry of
99mTc-RP527, a promising radioligand for the visualization of gastrin-releasing peptide …

Biodistribution and radiation dosimetry of [99mTc] Tc-N4-BTG: Initial experience

A Gaeble, A Rinscheid, G Wienand, D Euba… - 2023 - Soc Nuclear Med
P852 Introduction: In patients with prostate cancer (PC), imaging with gastrin releasing
peptide receptor (GRPR) ligands may be considered as an alternative to PSMA-targeted …

Clinical translation of a dual integrin αvβ3–and gastrin-releasing peptide receptor–targeting PET radiotracer, 68Ga-BBN-RGD

J Zhang, G Niu, L Lang, F Li, X Fan, X Yan… - Journal of Nuclear …, 2017 - Soc Nuclear Med
This study aimed to document the first-in-human application of a 68Ga-labeled
heterodimeric peptide BBN-RGD (bombesin-RGD) that targets both integrin αvβ3 and …

Biodistribution and dosimetry of 99mTc RP527, a gastrin releasing peptide agonist for the visualisation of GRP-receptor expressing malignancies

C Van de Wiele, F Dumont, RA Dierckx… - Nuclear Medicine …, 2000 - journals.lww.com
This study reports on the biodistribution and radiation dosimetry of 99m Tc RP527, a
radioligand for the visualisation of gastrin releasing (GRP) receptor expressing human …

Targeted imaging of gastrin-releasing peptide receptors with 99mTc-EDDA/HYNIC-[Lys3]-bombesin: biokinetics and dosimetry in women

CL Santos-Cuevas, G Ferro-Flores… - Nuclear medicine …, 2008 - journals.lww.com
Background The gastrin-releasing peptide receptor (GRP-R) is expressed in several normal
human tissues and is overexpressed in various human tumors including breast, prostate …

Preparation of 64Cu-NODAGA-RGD-BBN labeled compound and its absorbed dose estimation in humans based on mouse data

N Amraee, B Alirezapour, M Hosntalab… - Journal of Nuclear …, 2023 - jonsat.nstri.ir
Calculating the absorbed dose in the human body is one of the first steps in
radiopharmaceutical development. This study estimates the dose absorbed by humans from …