lipophilic statins in subjects with early mild cognitive impairment: Associations with conversion to dementia and decline in posterior cingulate brain metabolism in a …

P Padmanabham, S Liu, D Silverman - 2021 - Soc Nuclear Med
102 Objectives: Studies of the relationship between use of statins (HMG-CoA reductase
inhibitors) and subsequent cognitive performance have been variously reported to …

Statins and cognitive function in the elderly: the Cardiovascular Health Study

C Bernick, R Katz, NL Smith, S Rapp, R Bhadelia… - Neurology, 2005 - AAN Enterprises
Objective: To examine the association of statin drug use on cognitive and MRI change in
older adults. Methods: Participants in the Cardiovascular Health Study, a longitudinal study …

Association of statin use with cognitive decline in elderly African Americans

SJ Szwast, HC Hendrie, KA Lane, S Gao, SE Taylor… - Neurology, 2007 - AAN Enterprises
Background: Previously reported associations between statin use and incident dementia or
cognitive decline have been inconsistent. We report the results from a 3-year prospective …

[CITATION][C] P4‐186: Longitudinal changes in brain function related to statin use

L Beason‐Held, M Thambisetty, M Kraut… - Alzheimer's & …, 2012 - Wiley Online Library
Background Previous studies have suggested a link between high cholesterol and
increased risk for Alzheimer's disease (AD). This link led to the proposal that cholesterol …

[CITATION][C] P2‐586: LIPOPHILIC STATIN USE ASSOCIATED WITH DEFICITS IN MEMORY AND COGNITION

AK Chan, L Fornazzari, AC Golas, J Barfett… - Alzheimer's & …, 2018 - Wiley Online Library
Background Despite being the most prescribed drug class in Canada, the effects of HMG-
CoA reductase inhibitors, or statins, on memory and cognition remain widely debated. Within …

Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study

C Cramer, MN Haan, S Galea, KM Langa… - Neurology, 2008 - AAN Enterprises
Objective: Evidence of a relation between use of lipid lowering drugs and cognitive
outcomes is mixed. This study aimed to test the association between use of statins and …

[HTML][HTML] The effect of statins on rate of cognitive decline in mild cognitive impairment

KB Smith, P Kang, MN Sabbagh… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction This study's aims are to identify whether a relationship between statin use and
rate of cognitive decline exists. The relationship between statins and mild cognitive …

Statins and cognitive decline in older adults with normal cognition or mild cognitive impairment

K Steenland, L Zhao, FC Goldstein… - Journal of the American …, 2013 - Wiley Online Library
Objectives To determine the effect of statins on cognitive decline in healthy elderly adults.
Design Longitudinal. Setting National I nstitute of A ging network of A lzheimer's D isease …

Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease

BA Evans, JE Evans, SP Baker, K Kane… - Dementia and geriatric …, 2009 - karger.com
Abstract Background/Aims: It is not yet established whether statins (lipophilic or hydrophilic)
reduce the risk of Alzheimer's disease and, if so, by differentially modifying brain lipid levels …

Lipid metabolism in cognitive decline and dementia

F Panza, A D'Introno, AM Colacicco, C Capurso… - Brain research …, 2006 - Elsevier
This review will focus on the current knowledge on circulating serum and plasma risk factors
of cognitive decline of degenerative (Alzheimer's disease, AD) or vascular origin (vascular …