Imagesof the distrIbutionof a givennucildein a sectionof biologicaltissuecan be obtained at
the microscopic level by †œsecondary-ionmass analysis. ― in this method, the …

" Secondary ion emission analysis", a method of surface microanalysis proposed in 1960 by
Castaing and Slodzian, has been applied to the study of biological tissues by several groups …

The necessity of low temperature preparative procedures for diffusible ion localization using
the ion microscope has been established with rat liver as the test material. Using …

The method described in this paper incorporates the following desirable features: 1. It is
possible to prepare radioautographs from tissue that has been frozen and dehydrated in …

Elemental Imaging. Direct electronegative ion imaging was performed with a low current 10
keV Cs4@ primary beam (20— 30 nA) focusedon areas of 60 and 150@ in diameter. A …

494• ANALYTICAL CHEMISTRY, VOL. 58, NO. 2, FEBRUARY 1986 powerful technique for
such studies. The unique ion optics of the instrument are capable of producing ion images …

Analytical ion microscopy, a method proposed and developed in 1960 by Casting and
Slodzian at the Orsay University (France), makes it possible to obtain easily and rapidly …

Ion microscopy is a microanalytical method by which one can obtain distribution images of
any chemical element with isotope discrimination even at very low local concentrations, in …

The application of ion microanalysis (IMA) to the chemical characterization of freeze-fixed,
freeze-dried cells is reviewed. Particular emphasis is given to pathological studies involving …

326 LEVI-SETTI material. The signals that carry this information originate in secondary
atomic and electronic processes promoted by the impinging primary probe ions. Tn addition …