Radiolabeled monoclonal antibodies specific to the extracellular domain of prostate-specific membrane antigen: preclinical studies in nude mice bearing LNCaP …

PM Smith-Jones, S Vallabhajosula… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA), a transmembrane glycoprotein, is highly
expressed by virtually all prostate cancers. PSMA is also expressed on the tumor vascular …

In Vitro Characterization of Radiolabeled Monoclonal Antibodies Specific for the Extracellular Domain of Prostate-specific Membrane Antigen

PM Smith-Jones, S Vallabahajosula, SJ Goldsmith… - Cancer research, 2000 - AACR
Prostate-specific membrane antigen (PSMA) is a well-characterized cell surface antigen
expressed by virtually all prostate cancers (PCas). PSMA has been successfully targeted in …

Radioimmunotherapy of prostate cancer in human xenografts using monoclonal antibodies specific to prostate specific membrane antigen (PSMA): studies in nude …

S Vallabhajosula, PM Smith‐Jones, V Navarro… - The …, 2004 - Wiley Online Library
BACKGROUND Prostate specific membrane antigen (PSMA), expressed by virtually all
prostate cancers is an ideal target for targeted therapy of prostate cancer. Radiolabeled …

PET imaging of prostate cancer xenografts with a highly specific antibody against the prostate-specific membrane antigen

U Elsässer-Beile, G Reischl, S Wiehr… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA), a transmembrane glycoprotein, is highly
expressed by virtually all prostate cancers and is currently the focus of several diagnostic …

Location of prostate‐specific membrane antigen in the LNCaP prostate carcinoma cell line

JK Troyer, ML Beckett, GL Wright Jr - The Prostate, 1997 - Wiley Online Library
BACKGROUND Prostate-specific membrane antigen (PSMA) is a novel prostate biomarker
overexpressed in poorly differentiated and metastatic prostate carcinomas and apparently …

Prostate-specific membrane antigen (PSMA)-specific monoclonal antibodies in the treatment of prostate and other cancers

MC Gong, SS Chang, M Sadelain, NH Bander… - Cancer and Metastasis …, 1999 - Springer
Prostate-specific membrane antigen (PSMA) is a cell surface glycoprotein that is expressed
by prostate epithelial cells. PSMA-specific monoclonal antibodies have been utilized to …

A new generation of monoclonal and recombinant antibodies against cell‐adherent prostate specific membrane antigen for diagnostic and therapeutic targeting of …

U Elsässer‐Beile, P Wolf, D Gierschner, P Bühler… - The …, 2006 - Wiley Online Library
BACKGROUND Prostate‐specific membrane antigen (PSMA) is an excellent candidate for
targeting prostate cancer by virtue of its restricted expression on prostatic epithelial cells and …

A dual‐monoclonal sandwich assay for prostate‐specific membrane antigen: Levels in tissues, seminal fluid and urine

RL Sokoloff, KC Norton, CL Gasior, KM Marker… - The …, 2000 - Wiley Online Library
BACKGROUND Prostate‐specific membrane antigen (PSMA) is a 750‐residue integral
membrane glycoprotein and the target of an in‐vivo imaging agent for metastatic prostate …

Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: In vivo Imaging in Experimental Models of Prostate Cancer

CA Foss, RC Mease, H Fan, Y Wang, HT Ravert… - Clinical cancer …, 2005 - AACR
Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …

Monoclonal antibodies to the extracellular domain of prostate-specific membrane antigen also react with tumor vascular endothelium

H Liu, P Moy, S Kim, Y Xia, A Rajasekaran, V Navarro… - Cancer research, 1997 - AACR
Prostate-specific membrane antigen (PSMA), initially defined by monoclonal antibody (mAb)
7E11, is a now well-characterized type 2 integral membrane glycoprotein expressed in a …