1733 Objectives: We aimed to improve quantitative accuracy of time-activity curves (TACs) of
regional tissue from dynamic myocardial PET images. To this end, we proposed and …

OBJECTIVE: We purpose a novel factor analysis method based on kinetic cluster and α-
divergence measure for extracting the blood input function and the time-activity curve of the …

3188 Introduction: Dynamic cardiac positron emission tomography (PET) imaging extends
functional imaging by incorporating information from multiple time frames, as opposed to the …

Factor analysis has been pursued as a means to decompose dynamic cardiac PET images
into different tissue types based on their unique physiology. Each tissue is represented by a …

1772 Objectives: Dynamic myocardial perfusion PET imaging requires application of kinetic
modeling to time activity curves (TACs) generated at the voxel level, which can result in poor …

We propose a novel framework of robust kinetic parameter estimation applied to absolute
ow quanti cation in dynamic PET imaging. Kinetic parameter estimation is formulated as a …

Factor Analysis of Medical Image Sequences (FAMIS) estimates kinetics (factors) and
corresponding spatial regions (factor images) from dynamic studies, taking into account …

Purpose: Factor analysis has been pursued as a means to decompose dynamic cardiac PET
images into different tissue types based on their unique temporal signatures to improve …

Quantitative myocardial perfusion (MP) PET has the potential to enhance detection of early
stages of atherosclerosis or microvascular dysfunction, characterization of flow-limiting …

Dynamic PET myocardial perfusion imaging (MPI) used in conjunction with tracer kinetic
modeling enables the quantification of absolute myocardial blood flow (MBF). However …