[PDF] snmjournals.orgFree from Publisher

Temporal modulation of HER2 membrane availability increases pertuzumab uptake and pretargeted molecular imaging of gastric tumors

PMR Pereira, K Mandleywala… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Human epidermal growth factor receptor 2 (HER2) is used as a tumor biomarker and
therapeutic target. Pertuzumab is an anti-HER2 antibody, and its binding to tumor cells …
Save Cite Cited by 32 Related articles All 6 versions
[HTML] hindawi.com

[HTML][HTML] Comparative evaluation of radioiodine and technetium-labeled DARPin 9_29 for radionuclide molecular imaging of HER2 expression in malignant tumors

A Vorobyeva, O Bragina, M Altai, B Mitran… - Contrast Media & …, 2018 - hindawi.com
High expression of human epidermal growth factor receptor 2 (HER2) in breast and
gastroesophageal carcinomas is a predictive biomarker for treatment using HER2-targeted …
Save Cite Cited by 55 Related articles All 11 versions View as HTML
[PDF] snmjournals.orgFree from Publisher

Micro-SPECT/CT with 111In-DTPA-pertuzumab sensitively detects trastuzumab-mediated HER2 downregulation and tumor response in athymic mice bearing MDA …

K McLarty, B Cornelissen, Z Cai… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Pertuzumab is a HER2 dimerization inhibitor that binds to an epitope unique from that of
trastuzumab. Our objective was to determine whether SPECT with 111In …
Save Cite Cited by 90 Related articles All 14 versions
[HTML] springer.com

[HTML][HTML] Construction of 124I-trastuzumab for noninvasive PET imaging of HER2 expression: from patient-derived xenograft models to gastric cancer patients

X Guo, N Zhou, Z Chen, T Liu, X Xu, X Lei, L Shen… - Gastric Cancer, 2020 - Springer
Purpose Here, we sought to develop a PET radioligand based on trastuzumab labeled with
124 I, 124 I-trastuzumab, to evaluate its distribution, internal dosimetry, and initial PET …
Save Cite Cited by 29 Related articles All 5 versions
[PDF] snmjournals.orgFree from Publisher

Human epidermal growth factor receptor 3–specific tumor uptake and biodistribution of 89Zr-MSB0010853 visualized by real-time and noninvasive PET imaging

FJ Warnders, AGTT van Scheltinga… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The human epidermal growth factor receptor 3 (HER3) is an interesting target for antitumor
therapy. For optimal HER3 signaling inhibition, a biparatopic Nanobody construct …
Save Cite Cited by 41 Related articles All 7 versions
[HTML] mdpi.com

[HTML][HTML] HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

SS Rinne, CD Leitao, A Abouzayed, A Vorobyeva… - Cancers, 2021 - mdpi.com
Simple Summary HER3 is a known driver for oncogenesis and therapy resistance in solid
cancers. PET imaging could be a useful tool to non-invasively detect and monitor HER3 …
Save Cite Cited by 7 Related articles All 10 versions Cached
[HTML] nature.com

[HTML][HTML] Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model

WY Kuo, JJ Lin, HJ Hsu, HS Chen, AS Yang, CY Wu - Scientific reports, 2018 - nature.com
Human epidermal growth factor receptor 2 (HER2) overexpression occurs in various types of
cancers. Regarding the anti-HER2 targeted therapies showed superior treatment outcomes …
Save Cite Cited by 15 Related articles All 9 versions
[PDF] researchgate.net

Positron Emission Tomography Imaging with 18F-Labeled ZHER2:2891 Affibody for Detection of HER2 Expression and Pharmacodynamic Response to HER2 …

S Trousil, S Hoppmann, QD Nguyen, M Kaliszczak… - Clinical cancer …, 2014 - AACR
Purpose: Expression of HER2 has profound implications on treatment strategies in various
types of cancer. We investigated the specificity of radiolabeled HER2-targeting Z HER2 …
Save Cite Cited by 37 Related articles All 6 versions
[HTML] nih.gov

Immuno-PET Detects Antibody–Drug Potency on Coadministration with Statins

EL Brown, S Shmuel, K Mandleywala… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The human epidermal growth factor receptor 2 (HER2)–targeting trastuzumab emtansine (T-
DM1) and trastuzumab deruxtecan (T-DXd) are antibody–drug conjugates (ADC) clinically …
Save Cite Cited by 1 Related articles All 5 versions
[HTML] frontiersin.org

[HTML][HTML] Molecular imaging of HER2 receptor: Targeting HER2 for imaging and therapy in nuclear medicine

D Miladinova - Frontiers in molecular biosciences, 2023 - frontiersin.org
Targeting HER 2 for imaging and therapy in nuclear medicine has been used with a special
emphasis on developing more powerful radiopharmaceuticals. Zirconium-89 plays an …
Save Cite Cited by 8 Related articles All 5 versions Cached