Fluorine-18 labeled hydroxy quinoline derivatives as PET tracers for amyloid plaque imaging
P Kulkarni, N Vasdev, V Arora, G Hao, M Long, X Sun… - 2009 - Soc Nuclear Med
1188 Objectives To develop [18 F] labeled hydroxy quinoline derivatives for PET imaging of
amyloid plaques expressing elevated levels of metal ions. Methods 8-Benzyloxy-2 …
amyloid plaques expressing elevated levels of metal ions. Methods 8-Benzyloxy-2 …
PET imaging of Alzheimer's disease (AD) transgenic mice with a F-18 labeled hydroxy quinoline derivative
P Kulkarni, N Vasdev, V Arora, G Hao, M Long… - 2010 - Soc Nuclear Med
1746 Objectives To evaluate F-18 labeled 2-fluoro-8-hydroxy quinoline (HQ) for imaging
amyloid plaques in AD transgenic (Tg) mice with PET. Methods 8-benzyloxy-2 …
amyloid plaques in AD transgenic (Tg) mice with PET. Methods 8-benzyloxy-2 …
PET imaging of early stages of Alzheimer's disease (AD) in transgenic mice with F-18 hydroxy quinoline
1176 Objectives To evaluate F-18 labeled hydroxy quinoline (HOQ) in PET imaging of
plaques in AD transgenic (Tg) mice at early stages of the disease. Methods F-18 HOQ was …
plaques in AD transgenic (Tg) mice at early stages of the disease. Methods F-18 HOQ was …
[CITATION][C] IC‐P‐002: PET imaging of Alzheimer's disease (AD) transgenic mice with F‐18 labeled 8‐hydroxy quinoline
PV Kulkarni, N Vasdev, V Arora, G Hao… - Alzheimer's & …, 2010 - Wiley Online Library
Background Elevated levels of transition metal ions (Cu 2+ and Zn 2+) in Amyloid plaques
are potential targets. Weak metal chelator, hydroxyquinoline (HQ) derivatives are under …
are potential targets. Weak metal chelator, hydroxyquinoline (HQ) derivatives are under …
[PDF][PDF] IC-P-002 PET IMAGING OF ALZHEIMER'S DISEASE (AD) TRANSGENIC MICE WITH F-18 LABELED 8-HYDROXY QUINOLINE
INAS CATHEPSIN-D ACTIVITY - researchgate.net
Background: Elevated levels of transition metal ions (Cu2+ and Zn2+) in Amyloid plaques
are potential targets. Weak metal chelator, hydroxyquinoline (HQ) derivatives are under …
are potential targets. Weak metal chelator, hydroxyquinoline (HQ) derivatives are under …
18F-Labeled phenylquinoxaline compounds for PET imaging of Aβ plaques in Alzheimer's disease
1623 Objectives Beta-amyloid (Aβ) plaque is one of the most important characteristics of
Alzheimer's disease (AD). We have designed and prepared two novel 18F-labeled …
Alzheimer's disease (AD). We have designed and prepared two novel 18F-labeled …
[HTML][HTML] 18F-FPYBF-2, a new F-18-labelled amyloid imaging PET tracer: first experience in 61 volunteers and 55 patients with dementia
T Higashi, R Nishii, S Kagawa, Y Kishibe… - Annals of Nuclear …, 2018 - Springer
Objective Recently, we developed a benzofuran derivative for the imaging of β-amyloid
plaques, 5-(5-(2-(2-(2-18 F-fluoroethoxy) ethoxy) ethoxy) benzofuran-2-yl)-N-methylpyridin-2 …
plaques, 5-(5-(2-(2-(2-18 F-fluoroethoxy) ethoxy) ethoxy) benzofuran-2-yl)-N-methylpyridin-2 …
A New F‐18 Labeled PET Agent For Imaging Alzheimer's Plaques
PV Kulkarni, N Vasdev, G Hao, V Arora… - AIP Conference …, 2011 - pubs.aip.org
Amyloid plaques and neurofibrillary tangles are hallmarks of Alzheimer's disease (AD).
Advances in development of imaging agents have focused on targeting amyloid plaques …
Advances in development of imaging agents have focused on targeting amyloid plaques …
18F-labeled styrylpyridines as PET agents for amyloid plaque imaging
Positron emission tomography (PET) imaging of β-amyloid (Aβ) plaques in the brain is a
potentially valuable tool for studying the pathophysiology of Alzheimer's disease (AD). It may …
potentially valuable tool for studying the pathophysiology of Alzheimer's disease (AD). It may …
[18F] AP-05: A novel PET agent for in vivo detection of amyloid plaques in Alzheimer's disease patients
1880 Objectives We report here the synthesis and evaluation of a radiofluoro-pegylated
pyridylbenzoxazole derivative,[18F] AP-05 as imaging probe for cerebral β-amyloid (Aβ) …
pyridylbenzoxazole derivative,[18F] AP-05 as imaging probe for cerebral β-amyloid (Aβ) …