Sympathetic innervation of cold-activated brown and white fat in lean young adults

O Muzik, TJ Mangner, WR Leonard… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Recent work in rodents has demonstrated that basal activity of the local sympathetic nervous
system is critical for maintaining brown adipocyte phenotypes in classic brown adipose …

Differences in sympathetic nervous stimulation of brown adipose tissue between the young and old, and the lean and obese

L Bahler, HJ Verberne, WM Admiraal… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Brown adipose tissue (BAT) could facilitate weight loss by increasing energy expenditure.
Cold is a potent stimulator of BAT, activating BAT primarily through the sympathetic nervous …

Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure

WM Admiraal, F Holleman, L Bahler… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Brown adipose tissue (BAT) has become a focus of research in the hope of finding a new
target to fight obesity. Metabolic BAT activity can be visualized with 18F-FDG PET/CT …

[HTML][HTML] Brown Adipose Tissue Can Be Activated or Inhibited within an Hour before 18F-FDG Injection: A Preliminary Study with MicroPET

C Wu, W Cheng, H Xing, Y Dang, F Li… - BioMed Research …, 2011 - hindawi.com
Brown adipose tissue (BAT) is emerging as a potential target for treating human obesity. It
has been indicated that BAT is rich in innervations of sympathetic nerve control. Using 18 F …

15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat

O Muzik, TJ Mangner, WR Leonard… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Although it has been believed that brown adipose tissue (BAT) depots disappear shortly
after the perinatal period in humans, PET imaging using the glucose analog 18F-FDG has …

Fasting and postprandial activity of brown adipose tissue in healthy men

A Vrieze, JE Schopman, WM Admiraal… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The role of brown adipose tissue (BAT) in adult metabolism is poorly understood. This study
aimed to examine the differential effects of an overnight fast and the postprandial state on …

High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

M Saito, Y Okamatsu-Ogura, M Matsushita… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE The significant roles of brown adipose tissue (BAT) in the regulation of energy
expenditure and adiposity are established in small rodents but have been controversial in …

[18F] FDG and [11C] PK11195 PET imaging in the evaluation of brown adipose tissue-effects of cold and pharmacological stimuli and their association with crotamine …

D de Paula Faria, JDA Campeiro… - Nuclear Medicine and …, 2023 - Elsevier
This study aimed to evaluate the role of positron emission tomography (PET) with [11 C]
PK11195 and [18 F] FDG in the characterization of brown adipose tissue (BAT). Methods …

MRI reveals human brown adipose tissue is rapidly activated in response to cold

SM Oreskovich, FJ Ong, BA Ahmed… - Journal of the …, 2019 - academic.oup.com
Context In rodents, cold exposure induces the activation of brown adipose tissue (BAT) and
the induction of intracellular triacylglycerol (TAG) lipolysis. However, in humans, the kinetics …

18F-FDG PET/CT monitoring of β3 agonist–stimulated brown adipocyte recruitment in white adipose tissue

JW Park, KH Jung, JH Lee, CHT Quach… - Journal of Nuclear …, 2015 - Soc Nuclear Med
There is rising interest in recruitment of brown adipocytes into white adipose tissue (WAT) as
a means to augment energy expenditure for weight reduction. We thus investigated the …