Role of O-(2-18F-fluoroethyl)-L-tyrosine PET for differentiation of local recurrent brain metastasis from radiation necrosis

N Galldiks, G Stoffels, CP Filss, MD Piroth… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The aim of this study was to investigate the potential of O-(2-18F-fluoroethyl)-l-tyrosine (18F-
FET) PET for differentiating local recurrent brain metastasis from radiation necrosis after …

Dynamic O-(2-18F-fluoroethyl)-L-tyrosine positron emission tomography differentiates brain metastasis recurrence from radiation injury after radiotherapy

G Ceccon, P Lohmann, G Stoffels, N Judov… - Neuro …, 2017 - academic.oup.com
Background The aim of this study was to investigate the potential of dynamic O-(2-[18F]
fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis from …

18F-FET PET uptake characteristics in patients with newly diagnosed and untreated brain metastasis

M Unterrainer, N Galldiks, B Suchorska… - Journal of nuclear …, 2017 - Soc Nuclear Med
In patients with brain metastasis, PET using labeled amino acids has gained clinical
importance, mainly regarding the differentiation of viable tumor tissue from treatment-related …

[HTML][HTML] Suspected recurrence of brain metastases after focused high dose radiotherapy: can [18F]FET- PET overcome diagnostic uncertainties?

A Romagna, M Unterrainer, C Schmid-Tannwald… - Radiation …, 2016 - Springer
Background After focused high dose radiotherapy of brain metastases, differentiation
between tumor recurrence and radiation-induced lesions by conventional MRI is …

18F-FDOPA PET for differentiating recurrent or progressive brain metastatic tumors from late or delayed radiation injury after radiation treatment

KJ Lizarraga, M Allen-Auerbach, J Czernin… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Brain metastases are frequently treated with radiation. It is critical to distinguish recurrent or
progressive brain metastases (RPBM) from late or delayed radiation injury (LDRI). The …

Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from …

N Spaeth, MT Wyss, B Weber… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Differentiation between posttherapy radiation necrosis and recurrent tumor in humans with
brain tumor is still a difficult diagnostic task. The new PET tracers 18F-fluoro-ethyl-l-tyrosine …

Accuracy of F-DOPA PET and perfusion-MRI for differentiating radionecrotic from progressive brain metastases after radiosurgery

F Cicone, G Minniti, A Romano, A Papa… - European journal of …, 2015 - Springer
Purpose We assessed the performance of 6-[18 F]-fluoro-l-3, 4-dihydroxyphenylalanine (F-
DOPA) PET for differentiating radionecrosis (RN) from tumour progression (PD) in a …

[HTML][HTML] Prospective study of 11C–methionine PET for distinguishing between recurrent brain metastases and radiation necrosis: limitations of diagnostic accuracy …

S Yomo, K Oguchi - BMC cancer, 2017 - Springer
Background On conventional diagnostic imaging, the features of radiation necrosis (RN) are
similar to those of local recurrence (LR) of brain metastases (BM). 11 C–methionine positron …

Role of O-(2-18F-fluoroethyl)-L-tyrosine PET as a diagnostic tool for detection of malignant progression in patients with low-grade glioma

N Galldiks, G Stoffels, MI Ruge, M Rapp… - Journal of Nuclear …, 2013 - Soc Nuclear Med
In patients with low-grade glioma (LGG) of World Health Organization (WHO) grade II, early
detection of progression to WHO grade III or IV is of high clinical importance because the …

Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10

AM Allen, M Ben-Ami, A Reshef, A Steinmetz… - European journal of …, 2012 - Springer
Purpose Early assessment of tumor response to therapy is vital for treatment optimization for
the individual cancer patient. Induction of apoptosis is an early and nearly universal effect of …