Biodistribution studies of 89Zr-labeled nanodiamonds in mice using PET and MRI

N Eberhardt, J Loeffler, M Raabe, H Li, A Abaei… - 2020 - Soc Nuclear Med
1085 Objectives: Nanodiamonds (NDs) are of paramount interest for medical applications as
chemically-inert particles due to their biocompatibility [1]. NDs with nitrogen vacancies (NV …

[HTML][HTML] Preclinical PET and MR Evaluation of 89Zr- and 68Ga-Labeled Nanodiamonds in Mice over Different Time Scales

G Winter, N Eberhardt, J Löffler, M Raabe, MNA Alam… - Nanomaterials, 2022 - mdpi.com
Nanodiamonds (NDs) have high potential as a drug carrier and in combination with nitrogen
vacancies (NV centers) for highly sensitive MR-imaging after hyperpolarization. However …

Synthesis, radiolabeling, and preclinical in vivo evaluation of 68Ga-radiolabelled nanodiamonds

T Wanek, S Mairinger, M Raabe, MNA Alam… - Nuclear Medicine and …, 2023 - Elsevier
Abstract Purpose Nanodiamonds (NDs) represent a new class of nanoparticles and have
gained increasing interest in medical applications. Modifying the surface coating by …

Functionalized Nanodiamonds as Drug Delivery Agents: Pharmacokinetic and Biodistribution Studies

I Badea, R Rai, S Alwani, H Fonge - 2022 - papers.ssrn.com
Background: Nanodiamonds (NDs) are the most biocompatible members of the carbon nano-
family suitable for biomedical applications, including drug delivery1, 2. However, pristine …

Biodistribution of Nanodiamonds is Determined by Surface Functionalization

I Badea, R Rai, S Alwani, B Khan, R Vishwas… - Available at SSRN … - papers.ssrn.com
The purpose of study is to elucidate in vivo biodistribution of amino acid-functionalized
nanodiamonds (NDs, collectively 'fND'). Basic amino acid and di-peptide, lysine and lysyl …

Biodistribution of Amino-Functionalized Diamond Nanoparticles. In Vivo Studies Based on 18F Radionuclide Emission

S Rojas, JD Gispert, R Martin, S Abad, C Menchon… - ACS …, 2011 - ACS Publications
Nanoparticles have been proposed for several biomedical applications; however, in vivo
biodistribution studies to confirm their potential are scarce. Nanodiamonds are carbon …

Internalization and retention of nanodiamonds by MCF-7 cells in vitro: a potential drug delivery platform.

SA Khan, DZ Ivancic, T Zaichuk, H Huang, M Chen… - Cancer Research, 2009 - AACR
Abstract Abstract# 2134 Background: Selective uptake and prolonged retention of drugs will
facilitate pharmacotherapy to the breast. This may be accomplished by complexing of drugs …

Biodistribution of nanodiamonds is determined by surface functionalization

R Rai, S Alwani, B Khan, RV Solomon, S Vuong… - Diamond and Related …, 2023 - Elsevier
Solid-core nanoparticles made of carbon, metals and other inorganic materials are gaining
interest as nanocarriers to facilitate nucleic acid therapeutics. Our group designed amino …

Nanodiamonds doped with manganese for applications in magnetic resonance imaging

S Kunuku, BR Lin, CH Chen, CH Chang, TY Chen… - ACS …, 2023 - ACS Publications
Nanodiamonds (NDs) are emerging with great potential in biomedical applications like
biomarking through fluorescence and magnetic resonance imaging (MRI), targeted drug …

[HTML][HTML] Nanodiamond in cancer theranostics

Y Li, X Zhu, H Zhang, Y Lu, T Zeng, H Liu, T Li, J Wang… - Nano TransMed, 2023 - Elsevier
Nanodiamonds (NDs) are emerging as a promising platform for theranostic particles since
they offer a single platform that possesses multiple important properties. These include a …