Synthesis and evaluation of 2-[18F]-fluorobutyric acid as a PET tracer for imaging prostate cancer
NVK Pillarsetty, B Punzalan, T Ku, S Larson - 2009 - Soc Nuclear Med
1596 Objectives Recently we have discovered that a small carboxylic acid, 2-[18 F]-
fluoropropionic acid can be used for detecting prostate cancers. Our goal was to identify …
fluoropropionic acid can be used for detecting prostate cancers. Our goal was to identify …
2-18F-Fluoropropionic acid as a PET imaging agent for prostate cancer
NVK Pillarsetty, B Punzalan… - Journal of Nuclear …, 2009 - Soc Nuclear Med
There is a high interest in developing an 18F-labeled PET tracer that can aid in diagnosis
and therapy monitoring of prostate cancer. In the current study, we have evaluated the …
and therapy monitoring of prostate cancer. In the current study, we have evaluated the …
[18F]-NP3-029: A fluorine-18 labeled carboxylic acid for imaging prostate tumors
N Pillarsetty, P Blesida, E Santos, S Larson - 2008 - Soc Nuclear Med
196 Objectives: The short half life of [11 C]-Acetate has limited its use as a highly sensitive
marker for prostate and other non FDG avid tumors.[18 F]-Fluoroacetate has also been used …
marker for prostate and other non FDG avid tumors.[18 F]-Fluoroacetate has also been used …
MicroPET imaging with 2-[18F] fluoropropionic acid in Lewis lung carcinoma-bearing mice
Y Dang, J Cai, X Li, L Wang… - Chinese Journal of Nuclear …, 2016 - pesquisa.bvsalud.org
Objective To prepare 2-[18F] fiuoropropionic acid (18F-FPA) and evaluate its biodistribution
and imaging capacity in Lewis lung carcinoma-bearing mice. Methods 18F-FPA was …
and imaging capacity in Lewis lung carcinoma-bearing mice. Methods 18F-FPA was …
The preliminary feasibility studies of 4-[18F] fluorobutyric acid and its methyl ester as PET imaging agents
Y Dang, J Cai, L Wang, J Lv, F Li - International Journal of Radiation …, 2015 - inis.iaea.org
[en] Objective: To synthesize 4-[18 F] fluorobutyric acid and its methyl ester automatically
using PET-MF-2V-IT-I multifunction synthesizer and to evaluate their feasibility as PET …
using PET-MF-2V-IT-I multifunction synthesizer and to evaluate their feasibility as PET …
Imaging characteristics of [18F] GE-148 ([18F] FACBC) PET/CT in subjects with prostate cancer
J Sörensen, S Johansson, R Owenius, M Lax - 2010 - Soc Nuclear Med
457 Objectives Existing imaging techniques have limitations for the detection and staging of
prostate cancer. 1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ([18F] GE-148), also …
prostate cancer. 1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ([18F] GE-148), also …
[18F] GE-148 ([18F] FACBC) PET kinetics in subjects with prostate cancer and evaluation of simplified analysis methods
R Owenius, S Johansson, J Sörensen, M Lax - 2010 - Soc Nuclear Med
455 Objectives 1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ([18F] GE-148), also
known as [18F] FACBC, is a synthetic L-leucine analogue-based PET imaging agent that is …
known as [18F] FACBC, is a synthetic L-leucine analogue-based PET imaging agent that is …
Biological evaluation of PET/CT imaging agent 18F-fluoropropionic acid in hepatocellular carcinoma
J Zhao, N Jiang, S Liu, Z Zhang, H Ma… - International Journal of …, 2018 - inis.iaea.org
[en] Objective: To evaluate the potential of 18 F-fluoropiopionic acid (18 F-FPA) as a PET/CT
tracer in the imaging of hepatocellular carcinoma (HCC) and to identify the mechanism …
tracer in the imaging of hepatocellular carcinoma (HCC) and to identify the mechanism …
18F-fluoroacetate: a potential acetate analog for prostate tumor imaging—in vivo evaluation of 18F-fluoroacetate versus 11C-acetate
DE Ponde, CS Dence, N Oyama, J Kim… - Journal of nuclear …, 2007 - Soc Nuclear Med
PET with 11C-acetate (11C-ACE) has a high sensitivity for detection of prostate cancer and
several other cancers that are poorly detected with 18F-FDG. However, the short half-life …
several other cancers that are poorly detected with 18F-FDG. However, the short half-life …
Preclinical evaluation of 3-18F-fluoro-2, 2-dimethylpropionic acid as an imaging agent for tumor detection
Deregulated cellular metabolism is a hallmark of many cancers. In addition to increased
glycolytic flux, exploited for cancer imaging with 18F-FDG, tumor cells display aberrant lipid …
glycolytic flux, exploited for cancer imaging with 18F-FDG, tumor cells display aberrant lipid …
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