Access to diverse PET tracers for preclinical and clinical research remains a major obstacle
to research in cancer and other disease research. The prohibitive cost and limited …

Radiotracer synthesis is an ideal application for microfluidics because only nanogram
quantities are needed for positron emission tomography (PET) imaging. Thousands of …

We have developed an all-electronic digital microfluidic device for microscale chemical
synthesis in organic solvents, operated by electrowetting-on-dielectric (EWOD). As an …

Microscale radiosynthesis on a miniaturized device has been reported as a promising tool
for positron emission tomography. Here, we studied miscroscale-level radiosynthetic …

INTRODUCTION: 3′-Deoxy-3′-[18F] fluorothymidine ([18F] FLT) shows great potential as
a tracer for proliferative studies with PET. However, its regular application is often limited by …

We developed a new fully automated method for the synthesis of 3′-deoxy-3′-[18F]
fluorothymidine ([18F] FLT), by modifying a commercial FDG synthesizer and its disposable …

Abstract [18 F]-3′-deoxy-3′-fluorothymidine ([18 F] FLT) is an established positron
emission tomograph (PET)—radiopharmaceutical to study cell-proliferation rate in tumors …

Purpose The aim of this study was to develop a method of radiochemical synthesis of 3′-
deoxy-3′-[18 F] fluorothymidine ([18 F] FLT) with an improved radiochemical yield using …

AIM: To develop a simplified and fully automated synthesis procedure of 3′-deoxy-3′-
[18F] fluorothymidine ([18F] FLT) using PET-MF-2V-IT-I synthesis module. METHODS …

Current equipment and methods for preparation of radiopharmaceuticals for positron
emission tomography (PET) are expensive and best suited for large-scale multi-doses …