PSMA PET imaging in metastatic castration-resistant prostate cancer patients treated with 177Lu-PSMA-617: correlation with response, progression free (PFS) and …

MJ Niaz, M Sun, M Skafida, A Molina, J Babich… - 2020 - Soc Nuclear Med
191 Introduction: Targeted radionuclide therapy (TRT) is becoming an accepted treatment
modality for patients with advanced metastatic castration resistant prostate cancer (mCRPC) …

Pretherapeutic 68Ga-PSMA-617 PET may indicate the dosimetry of 177Lu-PSMA-617 and 177Lu-EB-PSMA-617 in main organs and tumor lesions

J Wang, J Zang, H Wang, Q Liu, F Li, Y Lin… - Clinical nuclear …, 2019 - journals.lww.com
Aim Combined 68 Ga-PSMA-617 PET imaging and 177 Lu-PSMA-617 therapy is a precise
targeted theranostic approach for patients with metastatic castration-resistant prostate …

First-in-human study of 177Lu-EB-PSMA-617 in patients with metastatic castration-resistant prostate cancer

J Zang, X Fan, H Wang, Q Liu, J Wang, H Li, F Li… - European journal of …, 2019 - Springer
Purpose This translational study is designed to assess the safety, dosimetry and therapeutic
response to a single, low-dose of 177 Lu-EB-PSMA-617 in comparison to 177 Lu-PSMA-617 …

Safety and response to177Lu-EB-PSMA-617 in patients with metastatic castration-resistant prostate cancer

J Zang, Q Liu, O Jacobson, G Niu, X Fan, Z Zhu… - 2019 - Soc Nuclear Med
536 Purpose: In prior studies, we synthesized 177 Lu-EB-PSMA by conjugating a truncated
Evans Blue (EB) molecule and DOTA chelator onto PSMA-617, and labeled it with 177 Lu …

177Lu-PSMA-617 in the Treatment of Castration-Resistant Prostate Cancer: Experience in Uruguay

H Silva, E Silvera, A Banchero, I Cordero… - World Journal of …, 2023 - thieme-connect.com
Methods: Prospective, analytical and experimental study of mCRPC patients who underwent
doses of 177 Lu-PSMA-617 (7.4 GBq every 6 weeks) at CUDIM in the period October …

Assessment of PSMA PET imaging response in metastatic castration-resistant prostate cancer after 225ac-J591 therapy: Post-hoc patient-level analysis of a …

A Ricaurte-Fajardo, A Martinez-Fundichel… - … Oncology: Seminars and …, 2024 - Elsevier
Introduction Prostate-specific membrane antigen (PSMA) targeted 225Ac shows promise for
metastatic castration-resistant prostate cancer (mCRPC) treatment. However, variations in …

[HTML][HTML] Targeting PSMA revolutionizes the role of nuclear medicine in diagnosis and treatment of prostate cancer

WI Luining, MCF Cysouw, D Meijer, NH Hendrikse… - Cancers, 2022 - mdpi.com
Simple Summary Imaging plays a crucial role in the accurate staging of prostate cancer.
Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer cells, and …

Extended therapy with Lu-177-PSMA-617 in patients with high tumor load metastatic castration-resistant prostate cancer

N Mader, J Baumgarten, D Groner, CN Ngoc, K Davis… - 2020 - Soc Nuclear Med
1276 Purpose: Treatment regimens with predefined treatment cycles of Lu-177-PSMA-617
radioligand therapy (RLT) may be suboptimal in patients with more aggressive high tumor …

[HTML][HTML] Prognostic implications of dual tracer PET/CT: PSMA ligand and [18F]FDG PET/CT in patients undergoing [177Lu]PSMA radioligand therapy

K Michalski, J Ruf, C Goetz, AK Seitz, AK Buck… - European Journal of …, 2021 - Springer
Background Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy
(RLT) with 177 Lu-labeled PSMA ligands has achieved remarkable results in advanced …

The prognostic value of posttreatment 68Ga-PSMA-11 PET/CT and 18F-FDG PET/CT in metastatic castration-resistant prostate cancer treated with 177Lu-PSMA-617 …

S Pathmanandavel, M Crumbaker… - Journal of Nuclear …, 2023 - Soc Nuclear Med
177Lu-PSMA-617 therapy has shown high prostate-specific antigen (PSA) response rates in
men with metastatic castration-resistant prostate cancer. However, early treatment …