2-((2 S, 5 R, 8 S, 11 S)-5-benzyl-8-(4-((2 S, 3 R, 4 R, 5 R, 6 S)-6-((2-(4-(3-18F-fluoropropyl)-
1H-1, 2, 3-triazol-1-yl) acetamido) methyl)-3, 4, 5-trihydroxytetrahydro-2H-pyran-2 …

Peptides containing the Arg-Gly-Asp (RGD) sequence have high affinity for αvβ3 integrin
receptors overexpressed in tumor cells. The objective of this research was to determine the …

18F-Galacto-RGD is a new tracer for PET imaging of αvβ3, a receptor involved in a variety of
pathologic processes including angiogenesis and metastasis. Our aim was to study the …

Abstract Purpose 99m Tc-3PRGD 2 is a 99m Tc-labeled dimeric cyclic RGD peptide with
increased receptor binding affinity and improved kinetics for in vivo imaging of integrin α v β …

The αvβ6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-
amino-acid αvβ6-binding peptide, derived from the foot and mouth virus …

Purpose To assess the safety, biodistribution, and dosimetric properties of the positron
emission tomography (PET) radiopharmaceutical agent fluorine 18 (18F) FPPRGD2 (2 …

The development of noninvasive methods to visualize and quantify integrin αvβ3 expression
in vivo appears to be crucial for the success of antiangiogenic therapy based on integrin …

We report the safety, biodistribution, and internal radiation dosimetry of a new PET tracer,
18F-AH111585, a peptide with a high affinity for the αvβ3 integrin receptor involved in …

αvβ3 integrins play an important role in angiogenesis and cell migration in cancer and are
highly expressed on the activated endothelial cells of newly formed blood vessels. Here, we …

INTRODUCTION: 68Ga-labeled RGD peptides in combination with PET allow non-invasive
determination of αvβ3 integrin expression which is highly increased during tumor-induced …