We aimed to explore whether the imaging of antiporter system xC− of immune cells with (4
S)-4-(3-18F-fluoropropyl)-l-glutamate (18F-FSPG) PET can assess inflammatory bowel …

Inflammatory bowel diseases (IBDs) in humans are characterized in part by aberrant CD4-
positive (CD4+) T-cell responses. Currently, identification of foci of inflammation within the …

Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disease
of the gastrointestinal tract. The diagnosis and monitoring of IBD are reliant on endoscopy …

We explored system x C− transporter activity and the detection of inflammatory or infectious
lesions using (4 S)-4-(3-18F-fluoropropyl)-l-glutamate (18F-FSPG) PET. Methods: In 10 …

In patients with inflammatory bowel disease (IBD) and in murine IBD models, mucosal
disease activity is routinely assessed by endoscopy and histologic evaluation. This …

Labeled leukocyte scintigraphy and 18 F-FDG PET are well-documented techniques for the
assessment of inflammatory bowel disease. In this study, a 28-year-old man with abdominal …

The aim of this study was development of an improved PET radiotracer for measuring xC−
activity with increased tumor uptake and reduced uptake in inflammatory cells compared …

Accurate, inexpensive, non-invasive studies in evaluation of inflammatory bowel disease
(IBD) would represent a significant advancement in identifying and measuring disease …

Purpose The purpose of the study was to validate [18 F] DPA-714, a translocator protein
(TSPO) 18 kDa radioligand, as a probe to non-invasively quantify the inflammatory state in …

Purpose The purpose of this study was to evaluate the appropriate 2-deoxy-2-[18 F] fluoro-d-
glucose–positron emission tomography (FDG-PET) determination in patients with …