PET/CT imaging of unstable carotid plaque with 68Ga-labeled somatostatin receptor ligand

MYS Wan, R Endozo, S Michopoulou… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68Ga-labeled somatostatin receptor ligand PET imaging has recently been shown in
preclinical and early human studies to have a potential role in the evaluation of vulnerable …

64Cu-DOTATATE PET/MRI for Detection of Activated Macrophages in Carotid Atherosclerotic Plaques: Studies in Patients Undergoing Endarterectomy

SF Pedersen, BV Sandholt, SH Keller… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—A feature of vulnerable atherosclerotic plaques of the carotid artery is high
activity and abundance of lesion macrophages. There is consensus that this is of importance …

Dual-tracer positron-emission tomography for identification of culprit carotid plaques and pathophysiology in vivo

NR Evans, JM Tarkin, MM Chowdhury… - Circulation …, 2020 - Am Heart Assoc
Background: Inflammation and microcalcification are interrelated processes contributing to
atherosclerotic plaque vulnerability. Positron-emission tomography can quantify these …

[HTML][HTML] Role of 18F-FDG positron emission tomography in carotid atherosclerotic plaque imaging: A systematic review

R Ravikanth - World Journal of Nuclear Medicine, 2020 - thieme-connect.com
Stroke and other thromboembolic events in the brain are often due to carotid artery
atherosclerosis, and atherosclerotic plaques with inflammation are considered particularly …

[HTML][HTML] Assessment of vulnerable atherosclerotic and fibrotic plaques in coronary arteries using 68Ga-DOTATATE PET/CT

A Mojtahedi, A Alavi, S Thamake… - American journal of …, 2015 - ncbi.nlm.nih.gov
Activated macrophages which express somatostatin receptor-2 (SSTR-2) play a vital role in
rupture of the vulnerable atherosclerotic plaques, which result in death. 68 Ga-DOTATATE …

Higher reliability of 18F-FDG target background ratio compared to standardized uptake value in vulnerable carotid plaque detection: a pilot study

A Niccoli Asabella, MM Ciccone, F Cortese… - Annals of nuclear …, 2014 - Springer
Objective To evaluate the role of [18F]-fluorodeoxyglucose positron emission
tomography/computer tomography [18F-FDG PET/CT] comparing target background ratio …

In vivo imaging of macrophage activity in the coronary arteries using 68Ga-DOTATATE PET/CT: correlation with coronary calcium burden and risk factors

A Rominger, T Saam, E Vogl, C Übleis… - Journal of nuclear …, 2010 - Soc Nuclear Med
We measured the uptake of the somatostatin receptor ligand 68Ga-[1, 4, 7, 10-
tetraazacyclododecane-N, N′, N ″, N′″-tetraacetic acid]-d-Phe1, Tyr3-octreotate …

When to image carotid plaque inflammation with FDG PET/CT

M Graebe, L Borgwardt, L Højgaard… - Nuclear medicine …, 2010 - journals.lww.com
Objective Quantification of 18-fluorodeoxyglucose (FDG) uptake in inflamed high-risk carotid
atherosclerotic plaques is challenged by the spatial resolution of positron emission …

64Cu-DOTATATE for noninvasive assessment of atherosclerosis in large arteries and its correlation with risk factors: head-to-head comparison with 68Ga-DOTATOC …

C Malmberg, RS Ripa, CB Johnbeck… - Journal of Nuclear …, 2015 - Soc Nuclear Med
The somatostatin receptor subtype 2 is expressed on macrophages, an abundant cell type in
the atherosclerotic plaque. Visualization of somatostatin receptor subtype 2, for oncologic …

Measurement of 68Ga-DOTATOC Uptake in the Thoracic Aorta and Its Correlation with Cardiovascular Risk

R Lee, J Kim, JC Paeng, JW Byun, GJ Cheon… - Nuclear Medicine and …, 2018 - Springer
Abstract Purpose 68 Ga-labeled 1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N‴-
tetraacetic acid-d-Phe 1-Tyr 3-octreotide (68 Ga-DOTATOC) is taken up by activated …