18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study

M Ogawa, S Ishino, T Mukai, D Asano… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The rupture of atherosclerotic plaques and the subsequent formation of thrombi are the main
factors responsible for myocardial and cerebral infarctions. Thus, the detection of vulnerable …

18F FDG uptake in the large arteries: a correlation study with the atherogenic risk factors

M Yun, S Jang, A Cucchiara, AB Newberg… - Seminars in nuclear …, 2002 - Elsevier
It has been reported that there is a high correlation between fluorodeoxyglucose (FDG)
uptake in the aorta and macrophage content of atherosclerotic lesions in an experimental …

What can be seen by 18F-FDG PET in atherosclerosis imaging? The effect of foam cell formation on 18F-FDG uptake to macrophages in vitro

M Ogawa, S Nakamura, Y Saito… - Journal of Nuclear …, 2012 - Soc Nuclear Med
18F-FDG PET is a promising tool for detecting vulnerable plaques, depending on the extent
of macrophage infiltration; however, it is still not clear which stage of the lesion can be …

Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques

M Ogawa, Y Magata, T Kato, K Hatano… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The rupture of atherosclerotic vulnerable plaques and subsequent formation of thrombi are
the main factors responsible for myocardial and cerebral infarctions. Because macrophage …

Imaging Atherosclerotic Plaque Inflammation With [18F]-Fluorodeoxyglucose Positron Emission Tomography

JHF Rudd, EA Warburton, TD Fryer, HA Jones… - Circulation, 2002 - Am Heart Assoc
Background—Atherosclerotic plaque rupture is usually a consequence of inflammatory cell
activity within the plaque. Current imaging techniques provide anatomic data but no …

F-18 FDG uptake in the large arteries: a new observation

M Yun, D Yeh, LI Araujo, S Jang… - Clinical nuclear …, 2001 - journals.lww.com
Purpose The cellular components of the atherosclerotic plaque, such as macrophages,
exhibits high glucose metabolic activity. The aim of this study was to show the frequency of …

[HTML][HTML] Non-invasive imaging of atherosclerotic plaque macrophage in a rabbit model with F-18 FDG PET: a histopathological correlation

Z Zhang, J Machac, G Helft, SG Worthley, C Tang… - BMC nuclear …, 2006 - Springer
Background Coronary atherosclerosis and its thrombotic complications are the major cause
of mortality and morbidity throughout the industrialized world. Thrombosis on disrupted …

Imaging of inflamed and vulnerable plaque in coronary arteries with 18F-FDG PET/CT in patients with suppression of myocardial uptake using a low-carbohydrate …

J Wykrzykowska, S Lehman, G Williams… - Journal of nuclear …, 2009 - Soc Nuclear Med
PET/CT imaging with 18F-FDG has been used to detect inflammation in carotid and aortic
plaque; its use in detecting coronary plaque has been limited by avid 18F-FDG uptake by …

18F-Choline Images Murine Atherosclerotic Plaques Ex Vivo

CM Matter, MT Wyss, P Meier, N Späth… - … , and vascular biology, 2006 - Am Heart Assoc
Objective—Current imaging modalities of atherosclerosis mainly visualize plaque
morphology. Valuable insight into plaque biology was achieved by visualizing enhanced …

Association of vascular 18F-FDG uptake with vascular calcification

MPS Dunphy, A Freiman, SM Larson… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Both calcification and FDG uptake have been advocated as indicators of atheroma.
Atheromas calcify as cells in the lesion undergo apoptosis and necrosis during evolution of …