Macrophage infiltration is a common characteristic feature of atherosclerotic-vulnerable
plaques. Macrophages recognize phosphatidylserine (PS) exposed on the surface of …

Introduction Previously, we reported a probe for imaging of atherosclerotic plaques: 111 In-
labeled liposomes. Liposomes were modified with phosphatidylserine (PS) because …

Exteriorized phosphatidylserine (PS) residues in apoptotic cells trigger rapid phagocytosis
by macrophage scavenger receptor pathways. Mimicking apoptosis with liposomes …

Liposomes are important carriers for controlling the spatial and temporal distribution of drug
molecules or other bioactive molecules. Radiolabeled liposomes have potential applications …

Radiolabeling of liposomes with 64Cu (t 1/2= 12.7 h) is attractive for molecular imaging and
monitoring drug delivery. A simple chelation procedure, performed at a low temperature and …

Liposomes have been used to diagnose and treat cancer and, to a lesser extent,
cardiovascular disease. We previously showed the uptake of anionic liposomes into the …

MATERIALS AND METHODS Liposome preparation. SUVs containing the ionophore
A23187 were prepared from distearoyl phosphatidyl choline (DSPC), cholesterol (CH) …

Atherosclerosis (AS) causes cardiovascular disease, which leads to fatal clinical end points
like myocardial infarction or stroke, the most prevalent causes of death in developed …

Apoptosis of macrophages and smooth muscle cells is linked to atherosclerotic plaque
destabilization. The apoptotic cascade leads to exposure of phosphatidylethanolamine (PE) …

Magnetic resonance (MR) imaging is becoming a pivotal diagnostic method to identify and
characterize vulnerable atherosclerotic plaques. We previously reported a reconstituted high …