1606 Objectives We assessed the defects of mitochondrial respiratory chain complexes in
relation to the degree of glycolysis in human HCCs. Methods Seventeen hepatocellular …

581 Objectives Mitochondrial dysfunction, rapid cell proliferation, enhanced glycolysis and a
hypoxic microenvironment are claimed to be characteristics of tumor aggressiveness and …

We conducted quantitative cellular respiration analysis on samples taken from human breast
cancer (HBC) and human colorectal cancer (HCC) patients. Respiratory capacity is not lost …

227 Objectives This study examined Warburg's hypothesis that mitochondria of cancer cells
are constitutively defective. FBnTP is an accurate marker of the mitochondrial membrane …

Malignancy is characterized by changes in energy production at the cellular level, and
metabolic alterations are used to detect and treat cancer. For example, the effectiveness of …

18F-FDG uptake in malignant tumors largely depends on the presence of facilitated glucose
transporters, especially type 1 (Glut 1) and a rate-limiting glycolytic enzyme, hexokinase …

Liver is the focal point of metabolic reactions in human body. It is an extremely active organ
executing carbohydrate, fat, and protein metabolism at higher rate. Malfunctioning of liver …

Alterations in the energy metabolism of cancer cells have been reported for many years.
However, the deleterious mechanisms involved in these deficiencies have not yet been …

Lung cancer killed 1.8 million people globally in 2020. In the United States, there will be
over 235,760 cases of lung cancer with an estimated death of 131,880 individuals in 2021 …

Background We explored the use of 4-[18F] fluorobenzyl triphenylphosphonium (18FTP) as
a mitochondrial-specific, voltage-sensitive positron emission tomography (PET) probe to …