11C-Pittsburgh Compound B (11C-PiB) PET has demonstrated significantly higher PiB
retention in the gray matter of Alzheimer disease (AD) patients than in healthy controls …

Objective: To compare brain β-amyloid (Aβ) burden measured with [11C] Pittsburgh
Compound B (PIB) PET in normal aging, Alzheimer disease (AD), and other dementias …

[11C] PIB (11C-6-OH benzothiazole) reflects the regional distribution of amyloid (beta-
sheeted proteins) in patients with Alzheimer's disease (AD). Proteinaceous inclusions in …

The positron emission tomography (PET) ligand 11C‐labeled Pittsburgh compound B (PIB)
is used to image β‐amyloid (Aβ) deposits in the brains of living subjects with the intent of …

Background: The PET tracer 11C-labeled Pittsburgh Compound-B (11C-PIB) specifically
binds fibrillar amyloid-beta (Aβ) plaques and can be detected in Alzheimer disease (AD). We …

11C-Pittsburgh Compound-B (11C-PIB) and 18F-(2-(1-{6-[(2-[18F] fluoroethyl)(methyl)
amino]-2-naphthyl} ethylidene)(18F-FDDNP) have been developed as PET tracers for in …

Abstract Radiolabeled Pittsburgh compound B (PIB) is a benzothiazole imaging agent that
usually binds with high affinity, specificity, and stoichiometry to cerebral β-amyloid (Aβ) in …

The positron emission tomography (PET) radiotracer Pittsburgh Compound-B (PiB) binds
with high affinity to β-pleated sheet aggregates of the amyloid-β (Aβ) peptide in vitro. The in …

BACKGROUND: The positron emission tomography (PET) tracer [11C]-Pittsburgh
Compound-B ([11C] PIB) allows the in vivo assessment of amyloid plaque burden in the …

Context A progressive decline in episodic memory affecting activities of daily living is the
usual clinical presentation of Alzheimer disease. However, patients presenting with atypical …