Herein we aimed to evaluate the utility of N-(2, 5-dimethoxybenzyl)-2-18F-fluoro-N-(2-
phenoxyphenyl) acetamide (18F-PBR06) for detecting alterations in translocator protein …

Purpose Imaging the 18-kDa translocator protein (TSPO) is considered a potential tool for in
vivo evaluation of microglial activation and neuroinflammation in the early stages of …

Introduction Neuroinflammation is associated with several neurological disorders, including
Alzheimer's disease (AD). The translocator protein 18 kDa (TSPO), due to its overexpression …

The 18 kDa translocator protein (TSPO) is a widely used target for microglial PET imaging
radioligands, but its expression in post‐mortem normal and diseased human brain is not …

Purpose In this study we compared the recently developed TSPO tracer [18 F] F-DPA, with
[18 F] DPA-714 and [11 C] PBR28 by performing in vivo PET imaging on the same …

Microglial activation is a key pathological feature of Alzheimer's disease (AD). PET imaging
of translocator protein 18 kDa (TSPO) is a strategy to detect microglial activation in vivo …

Purpose Imaging of the 18-kDa translocator protein (TSPO) is a potential tool for examining
microglial activation and neuroinflammation in early Alzheimer's disease (AD).[18 F] FEMPA …

A substantial and constitutive expression of translocator protein (TSPO) in cerebral blood
vessels hampers the sensitive detection of neuroinflammation characterized by greatly …

[18F] F-DPA, a novel translocator protein 18 kDa (TSPO)-specific radioligand for imaging
neuroinflammation, has to date been synthesized with low to moderate molar activities …

Microglial activation has been linked with deficits in neuronal function and synaptic plasticity
in Alzheimer's disease (AD). The mitochondrial translocator protein (TSPO) is known to be …