Quantitative imaging of apoptosis using 99mTc-labeled annexin V in rheumatoid arthritis
challenges our conventional thinking on how disease progression or remission should be …

Rheumatoid arthritis is associated with chronic synovial inflammation due to the abnormal
accumulation of macrophages and autoreactive T lymphocytes in joints. The autoreactive …

We examined the accumulation of Cy5. 5-labeled annexin V in the paws of mice with and
without collagen-induced arthritis, with and without methotrexate (MTX) treatment, by near …

As remission has now become a realistic therapeutic goal in the clinical management of RA
due to the introduction and widespread adoption of biologic agents, there is a greater need …

Advanced imaging techniques are promising tools to assist in the early diagnosis and
monitoring of therapy in various rheumatic diseases. As there is now increasing emphasis …

Rheumatic disorders comprise a number of diseases that range from benign, mildly
symptomatic degenerative disease to severe systemic disorders such as giant-cell vasculitis …

Radionuclide detection of apoptosis with of 99mTc-Hynic-rh-Annexin V scintigraphy is an
effective tool for in vivo visualisation and monitoring of apoptosis in various malignant …

OBJECTIVES To investigate whether apoptosis occurs in osteoarthritis (OA), and if this
phenomenon is modulated by human recombinant interleukin 1β (hrIL1β). METHODS …

Single-photon-emission computed tomography (SPECT), a method for reconstructing cross-
sectional images of radiotracer distributions, was developed more than a quarter of a …

TO THE EDITOR: The recent paper in the Journal of Nuclear Medicine by Mochizuki et al.(1),
concerning the targeting of 99mTc-annexin V to apoptotic cells in a tumor xenograft, is …