The expression of claudin-4, a protein involved in tight junction complexes, is widely
dysregulated in epithelial malignancies. Claudin-4 is overexpressed in several premalignant …

Overexpression of tight-junction protein claudin-4 has been detected in primary and
metastatic pancreatic cancer tissue and is associated with better prognosis in patients …

We performed a comprehensive immunohistochemical evaluation of claudin 4 protein
expression in paraffin-embedded tissue samples from 72 patients with primary infiltrating …

Purpose Despite its widespread use, the positron emission tomography (PET) radiotracer 2-
deoxy-2-[18 F] fluoro-D-glucose ([18 F] FDG) has been shown in clinical settings to be …

Objectives Novel imaging methods based on specific molecular targets to detect both
established neoplasms and their precursor lesions are highly desirable in cancer medicine …

Since pancreatic cancer is often diagnosed in a late state of cancer development, diagnostic
opportunities allowing early disease detection are highly sought after. As such, cancer …

Abstract Claudin18. 2 (CLDN18. 2) is a tight junction protein that is overexpressed in a
variety of solid tumors such as gastrointestinal cancer and oesophageal cancer. It has been …

Claudin3 is an integral component of the tight junction proteins in polarized epithelia. The
expression of claudin3 was assessed in epithelial-derived tumors using Oncomine …

The majority of malignant tumors originate from epithelial cells, and many of them are
characterized by an overexpression of claudins (Cldns) and their mislocalization out of tight …

Purpose: The purpose of this study was to evaluate the capability of u-SPECT-II/CT to
monitor the progression of breast cancer lung metastasis using 99m Tc-3P-RGD 2 as a …