484 Objectives The brain serotonin (5-HT) system is involved in the regulation of appetite. In
animal models, a hyposerotonergic state leads to increased food intake and weight gain. We …

18 Objectives: The neurotransmitter serotonin contributes to the regulation of a number of
important physiological processes, including appetite. Disturbances in the distribution and/or …

16 Objectives 5-HT4 receptors are involved in memory and learning, and 5-HT4 agonism is
presumed to reduce accumulation of cerebral β-amyloid in Alzheimer's disease (AD) …

Purpose The role of the central serotonin (5-hydroxytryptamine, 5-HT) system in feeding has
been extensively studied in animals with the 5-HT family of transporters (5-HTT) being …

Methods Four obese subjects (mean age 37.9, range 31.8–49.4, 3 females) with BMI≥ 35
(mean 40.5 kg/m 2) were included in the study of the 5-HT 2A receptor and 4 obese subjects …

Previous imaging studies have suggested that there is an age-related decline in brain
serotonin (5-hydroxytryptamine) measures in healthy subjects. This paper addresses …

Materials and methods: 76 healthy volunteers (age: 43.6 T 17.4, range: 18–79 years, 36
females) were investigated with [18F]-altanserin PET and MRI. None of the subjects had a …

Manipulations of the serotonin levels in the brain can affect impulsive behavior and
influence our reactivity to conditioned reinforcers. Eating, tobacco smoking, and alcohol …

Indirect estimations of brain neurotransmitters in patients with anorexia nervosa (AN) and
low weight have demonstrated a reduction in brain serotonin (5-HT) turnover in general and …

1142 Objectives: Serotonin transporter (SERT) density is probably to a large extent
determining endogenous serotonin levels and the postsynaptic serotonin 2A (5-HT2A) …