Comparative biodistribution and radiation dosimetry of 68Ga-DOTATOC and 68Ga-DOTATATE in patients with neuroendocrine tumors

M Sandström, I Velikyan… - Journal of Nuclear …, 2013 - Soc Nuclear Med
68Ga-DOTATOC and 68Ga-DOTATATE are 2 radiolabeled somatostatin analogs for in vivo
diagnosis of neuroendocrine tumors with PET. The aim of the present work was to measure …

In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours—impact of peptide mass

I Velikyan, A Sundin, B Eriksson, H Lundqvist… - Nuclear medicine and …, 2010 - Elsevier
OBJECTIVES: The aim of this pilot study was to explore the impact of peptide mass on
binding of [68Ga]-DOTATOC to neuroendocrine tumour somatostatin receptors in vivo using …

Measured human dosimetry of 68Ga-DOTATATE

RC Walker, GT Smith, E Liu, B Moore… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Measured human dosimetry of the 68Ga-labeled synthetic somatostatin analog 68Ga-
DOTATATE has not been reported in the peer-reviewed literature. 68Ga-DOTATATE is an …

Radiation exposure of patients during 68Ga-DOTATOC PET/CT examinations

H Hartmann, K Zöphel, R Freudenberg… - Nuklearmedizin …, 2009 - thieme-connect.com
Aim: Investigation of the biodistribution and calculation of dosimetry of Ga-68-DOTATOCfor
patients imaged in the routine clinical setting for diagnosis or exclusion of neuroendocrine …

68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT

M Gabriel, C Decristoforo, D Kendler… - Journal of nuclear …, 2007 - Soc Nuclear Med
The aim of this study was to evaluate the diagnostic value of a new somatostatin analog,
68Ga-labeled 1, 4, 7, 10-tetraazacyclododecane-N, N′, N ″, N ″′-tetraacetic acid-d …

Treatment with octreotide does not reduce tumor uptake of 68Ga-DOTATATE as measured by PET/CT in patients with neuroendocrine tumors

AR Haug, A Rominger, M Mustafa… - Journal of Nuclear …, 2011 - Soc Nuclear Med
We hypothesized that 68Ga-DOTATATE uptake of neuroendocrine tumors is sensitive to
therapy with a nonradioactive somatostatin analog. Methods: 68Ga-DOTATATE PET/CT was …

[HTML][HTML] Peptide receptor radionuclide therapy of neuroendocrine tumors with 90Y-DOTATOC: is treatment response predictable by pre-therapeutic uptake of 68Ga …

MÖ Öksüz, L Winter, C Pfannenberg, G Reischl… - Diagnostic and …, 2014 - Elsevier
Abstract Purpose PET with 68 Ga-DOTATOC allows for imaging and quantitative
assessment of somatostatin receptor expression in neuroendocrine tumors (NET). The aim …

Semiquantitative analysis and characterization of physiological biodistribution of 68Ga-DOTA-TATE PET/CT

J Kunikowska, L Królicki, D Pawlak… - Clinical nuclear …, 2012 - journals.lww.com
The aim of this study was to describe the normal physiological distribution of 68 Ga-DOTA-
TATE using the SUV to reflect the density of somatostatin receptors in various organ …

Validation of 68Ge/68Ga generator processing by chemical purification for routine clinical application of 68Ga-DOTATOC

M Asti, G De Pietri, A Fraternali, E Grassi… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: Imaging of somatostatin receptor expressing tumours has been greatly
enhanced by the use of 68Ga-DOTATOC and PET/CT. METHODS: In this work, a purification …

68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor–mediated radionuclide therapy

M Gabriel, A Oberauer, G Dobrozemsky… - Journal of Nuclear …, 2009 - Soc Nuclear Med
68Ga-labeled 1, 4, 7, 10-tetraazacyclododecane-N, N′, N′′, N′′′-tetraacetic acid-d-
Phe1-Tyr3-octreotide (DOTA-TOC) PET has proven its usefulness in the diagnosis of …