The present translational study aimed to verify whether serial 18F-FDG PET/CT predicts
doxorubicin cardiotoxicity. Methods: Fifteen athymic mice were treated intravenously with …

Background—We sought to determine whether cardiovascular magnetic resonance
measures of gadolinium (Gd) signal intensity (SI) within the left ventricular myocardium are …

Background Cancer patients undergoing Doxorubicin (DOX) treatment are susceptible to
acute and chronic cardiac anomalies, including aberrant arrhythmias, ventricular …

Background Oxidative stress and its interference on myocardial metabolism play a major
role in Doxorubicin (DXR) cardiotoxic cascade. Methods Mice models of neuroblastoma …

AIM: To analyze changes in myocardial glucose metabolism using fluorodeoxyglucose
(FDG)-positron emission tomography (PET) in patients treated with adriamycin and to …

Background Doxorubicin is a cornerstone in lymphoma treatment, but is limited by dose-
dependent cardiotoxicity. Rubidium-82 positron emission tomography (82 Rb PET) …

Conclusion Doxorubicin cardiotoxicity has posed a formidable challenge in the fields of
oncology, cardiology, pharmacology, biochemistry, pathology, and molecular biology …

Background The aim of this study was to investigate changes in myocardial uptake
evaluated by oncologic 18 F-fluorodeoxyglucose (FDG) PET/CT scans and to determine the …

Despite its well-known cardiotoxicity, doxorubicin continues to be an effective and widely
used antineoplastic agent. Many efforts have focused on understanding the mechanism of …

Purpose: The aim was to investigate in patients receiving doxorubicin whether any alteration
in myocardial oxidative metabolism or blood flow as assessed by positron emission …