Imaging of intranuclear epitopes using antibodies tagged to cell-penetrating peptides has
great potential given its versatility, specificity, and sensitivity. However, this process is …

While radiolabelled antibodies have found great utility as PET and SPECT imaging agents
in oncological investigations, a notable shortcoming of these agents is their propensity to …

To optimize in vivo tissue uptake kinetics and clearance of engineered monoclonal antibody
(mAb) fragments for radiotherapeutic and radiodiagnostic applications, we compared the …

Longitudinal imaging of intratumoral distributions of antibodies in vivo in mouse cancer
models is of great importance for developing cancer therapies. In this study, multipinhole …

Purpose Although lymphocyte activation gene-3 (LAG-3) directed therapies demonstrate
promising clinical anti-cancer activity, only a subset of patients seems to benefit and …

Antibody-based dual-modality (PET/fluorescence) imaging enables both presurgery antigen-
specific immuno-PET for noninvasive whole-body evaluation and intraoperative …

1608 Objectives: Immuno Positron Emission Tomography (immunoPET) is utilised for
improving the detection and quantitation of the biodistribution properties of chimeric …

Pancreatic cancer has a high mortality rate due to late diagnosis and the tendency to invade
surrounding tissues and metastasize at an early stage. A molecular imaging agent that …

Abstract 18F-Fluorodeoxyglucose (18F-FDG) is the most common molecular imaging agent
in oncology, with a high sensitivity and specificity for detecting several cancers. Antibodies …

The Insulin-like growth factor-1 receptor (IGF-1R) is a molecular target for several
monoclonal antibodies undergoing clinical evaluation as anticancer therapeutics. The non …