PET and SPECT using appropriate radioligands allow imaging of certain critical components
of neurotransmission such as presynaptic transporters and postsynaptic receptors in living …

The science of quantitative analysis of PET and SPECT neuroreceptor imaging studies has
grown considerably over the past decade. A number of methods have been proposed in …

Over the past decade, a number of new kinetic modeling techniques have been developed
for PET and SPECT ligands. This article will review commonly used modeling solutions for …

A kinetic modeling approach for the quantification of in vivo tracer studies with dynamic
positron emission tomography (PET) is presented. The approach is based on a general …

Receptors have a prominent role in brain function, as they are the effector sites of
neurotransmission at the postsynaptic membrane, have a regulatory role on presynaptic …

This Fourth Edition reflects the significant recent progress that has occurred in the field of
functional brain imaging, particularly the increased use of PET/SPECT, the use of SPECT …

A wide range of study designs can be used with positron emission tomography methods to
provide quantitative measurements of physiological parameters. While bolus injection of …

Over the last decade, a large number of radiotracers have been developed to image and
quantify transporter availability with positron emission tomography (PET) or single-photon …

Dopaminergic ligands labeled with positron-emitting radionuclides have been synthesized
for quantitative evaluation of dopaminergic binding in vivo. Two different methods, the …

A method is presented for the generation of parametric images of radioligand–receptor
binding using PET. The method is based on a simplified reference region compartmental …