Visualization of myocardial phosphoinositide turnover with 1-[1-11C]-butyryl-2-palmitoyl-rac-glycerol in rats with myocardial infarction

M Chida, Y Kagaya, Y Imahori… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Phosphoinositide turnover mediates the signaling of angiotensin II, which plays a pivotal
role in ventricular remodeling after myocardial infarction (MI). We tested the hypothesis that …

Effect of angiotensin converting enzyme inhibition on myocardial phosphoinositide metabolism visualised with 1-[1-11C]-butyryl-2-palmitoyl-rac-glycerol in …

Y Kagaya, M Chida, Y Imahori, R Fujii… - European Journal of …, 2002 - Springer
We recently reported that myocardial phosphoinositide (PI) metabolism can be visualised by
1-[1-11 C]-butyryl-2-palmitoyl-rac-glycerol (11 C-DAG) in rats with myocardial infarction (MI) …

Myocardial 11C-diacylglycerol accumulation and left ventricular remodeling in patients after myocardial infarction

H Otani, Y Kagaya, Y Imahori, S Yasuda… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Left ventricular (LV) remodeling after myocardial infarction (MI) is a maladaptive process that
increases the risk of heart failure and death. The myocardial phosphoinositide cycle, which …

[18F] labeled diacylglycerol analogue as a potential agent to trace myocardial phosphoinositide metabolism

M Chida, Y Kagaya, S Nagata, M Mukoyoshi… - Nuclear medicine and …, 2001 - Elsevier
Phosphoinositide metabolism plays an important role in cardiac pathophysiology. To
investigate whether [18F] diacylglycerol could be used to trace myocardial phosphoinositide …

Serial change of 123I-BMIPP SPECT imaging during recovery from stunned myocardium after acute myocardial infarction--correlation with 201Tl and two-dimensional …

A Nakano, M Kondo, S Tokunaga… - Kaku igaku. The …, 1995 - europepmc.org
Using 123I-beta-methyl iodophenyl pentadecanoic acid (123I-BMIPP), we investigated
changes in myocardial fatty acid metabolism at recovery from stunned myocardium after …

Evaluation of cellular viability by quantitative autoradiographic study of myocardial uptake of a fatty acid analogue in isoproterenol-induced focal rat heart necrosis

T Humbert, C Luu-Duc, M Comet… - European journal of …, 1991 - Springer
Previous studies led us to hypothesize that a fatty acid analogue, 15-p-iodophenyl-β-methyl
pentadecanoic acid (IMPPA or BMIPP), which is taken up but not quickly metabolized by …

Serial evaluation of fatty acid metabolism in rats with myocardial infarction by pinhole SPECT

T Hirai, R Nohara, S Ogoh, LG Chen, K Kataoka… - Journal of nuclear …, 2001 - Elsevier
Background. Iodine 123-labeled 15-(p-iodophenyl)-3-(R, S)-methylpentadecanoic acid
(BMIPP) is mainly trapped in the myocardium as triglyceride, depending on the adenosine …

Value of fatty acid imaging using 123I-beta-methyl iodophenyl pentadecanoic acid (BMIPP) to assess viability of infarcted myocardium

M Kawamoto, N Tamaki, Y Yonekura… - Kaku igaku. The …, 1991 - europepmc.org
To evaluate clinical value of a new fatty acid imaging tracer, 123I-beta-methyl iodophenyl
pentadecanoic acid (BMIPP), 27 patients with myocardial infarction (MI) underwent BMIPP …

Simultaneous evaluation of myocardial perfusion and fatty acid metabolism using dynamic SPECT with single injection of 123I-15-(p-iodophenyl)-3-methyl …

H Kobayashi, R Asano, T Oka, S Inoue… - Kaku igaku. The …, 1995 - europepmc.org
The purpose of this study is to clarify whether dynamic SPECT (DECT) immediately after the
injection of 123I-15-(p-iodophenyl)-3-methyl pentadecanoic acid (BMIPP) may represent …

Clinical usefulness of iodine 123-labeled fatty acid imaging in patients with acute myocardial infarction

H Naruse, T Arii, T Kondo, M Morita… - Journal of Nuclear …, 1998 - Springer
Background Iodine 123-labeled 15-(p-iodophenyl)-3R, S-methylpentadecanoic acid
(BMIPP) has recently been developed, since normal myocardium metabolizes free fatty …