Preserved coronary flow reserve effectively excludes high-risk coronary artery disease on angiography

M Naya, VL Murthy, VR Taqueti, CR Foster… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Myocardial perfusion imaging has limited sensitivity for the detection of high-risk coronary
artery disease (CAD). We tested the hypothesis that a normal coronary flow reserve (CFR) …

Absolute flow or myocardial flow reserve for the detection of significant coronary artery disease?

E Joutsiniemi, A Saraste, M Pietilä… - European Heart …, 2014 - academic.oup.com
Objectives We compared the accuracy of quantified myocardial flow reserve and absolute
stress myocardial blood flow (MBF) alone in the detection of coronary artery disease (CAD) …

Does quantification of myocardial flow reserve using rubidium-82 positron emission tomography facilitate detection of multivessel coronary artery disease?

MC Ziadi, RA Dekemp, K Williams, A Guo… - Journal of Nuclear …, 2012 - Springer
Background Relative myocardial perfusion imaging (MPI) is the standard imaging approach
for the diagnosis and prognostic work-up of coronary artery disease (CAD). However, this …

Prediction of short-term cardiovascular events using quantification of global myocardial flow reserve in patients referred for clinical 82Rb PET perfusion imaging

K Fukushima, MS Javadi, T Higuchi… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Current noninvasive tests for coronary artery disease detect atherosclerosis or regional
ischemia. Global myocardial flow reserve is not routinely identified, although it may be an …

Clinical decision making with myocardial perfusion imaging in patients with known or suspected coronary artery disease

P Cremer, R Hachamovitch, B Tamarappoo - Seminars in nuclear medicine, 2014 - Elsevier
Myocardial perfusion imaging (MPI) to diagnose coronary artery disease (CAD) is best
performed in patients with intermediate pretest likelihood of disease; unfortunately, pretest …

Quantitative assessment of myocardial perfusion in the detection of significant coronary artery disease: cutoff values and diagnostic accuracy of quantitative [15O] H2O …

I Danad, V Uusitalo, T Kero, A Saraste… - Journal of the American …, 2014 - jacc.org
Background: Recent studies have demonstrated improved diagnostic accuracy for detecting
coronary artery disease (CAD) when myocardial blood flow (MBF) is quantified in absolute …

Relative flow reserve derived from quantitative perfusion imaging may not outperform stress myocardial blood flow for identification of hemodynamically significant …

WJ Stuijfzand, V Uusitalo, T Kero, I Danad… - Circulation …, 2015 - Am Heart Assoc
Background—Quantitative myocardial perfusion imaging is increasingly used for the
diagnosis of coronary artery disease. Quantitative perfusion imaging allows to noninvasively …

Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: a study using oxygen 15 …

K Yoshinaga, C Katoh, K Noriyasu, Y Iwado… - Journal of nuclear …, 2003 - Springer
Background Myocardial perfusion single photon emission computed tomography (SPECT)
occasionally fails to detect coronary stenosis in patients with coronary artery disease (CAD) …

Global coronary flow reserve is associated with adverse cardiovascular events independently of luminal angiographic severity and modifies the effect of early …

VR Taqueti, R Hachamovitch, VL Murthy, M Naya… - Circulation, 2015 - Am Heart Assoc
Background—Coronary flow reserve (CFR), an integrated measure of focal, diffuse, and
small-vessel coronary artery disease (CAD), identifies patients at risk for cardiac death. We …

Functional stress imaging to predict abnormal coronary fractional flow reserve: the PACIFIC 2 study

RS Driessen, PA van Diemen… - European heart …, 2022 - academic.oup.com
Aims The diagnostic performance of non-invasive imaging in patients with prior coronary
artery disease (CAD) has not been tested in prospective head-to-head comparative studies …