Tissue distribution studies of CL-19.1311 and NCL-6-'311. The above facts, therefore,
induced us to make a comparison of the accumulation of very pure CL-19-'311 and NCL-6 …

MATERIALS AND METHODS Radiopharmaceutical. Figure 1 shows the chemical structures
of 131@ 44p_59and 1311-19-iodocholesterol. Using the method of Basmadjian, et al (12) …

MATERIALS AND METHODS Hydrogen cyanide labeled with 20.4-mm 11Cwas produced
by cyclotron bombardment of a gas target, 99% N2 and 1% H2, with 22-MeV protonsusing …

PRELIMINARY NOTE Imaging the Adrenal Medulla with an 1-131-labeled Antladrenerglc Agent
Page 1 Adrenal-medullary imaging agents have been ac tively pursued by our laboratory and …

The chapters herein are updated and expanded versions of presentations that the authors
made at a symposium held on June 4, 1984 in Los Angeles, California under the …

The two adrenal-specific compounds, 19-iodocholest-5-en-3ß-ol (19-iodocholesterol) and
6ß-iodomethyl-19-norcholest-5 (10)-en-3ß-ol (6-iodomethylnorcholesterol), synthesized …

We have reported tissue distribution studies in rats and dogs with a new adrenal imaging
agent, l31I-6ß3-iodomethyl–19-nor-cholesterol (NP-59). This agent concentrated five times …

A new adrenal cortex imaging agent. 6β‐131 I‐iodomethyl‐19‐norcholest‐5 (10)‐en‐3β‐ol
(NP‐59)[I] was synthesized by the homallylic rearrangement of 19‐iodocholesterol or …

MATERIALS AND METHODS The Np-59 was prepared and administered as de scribed by
Freitas et al.(6). Adrenal uptake per centages were calculated on all patients using the …

“Minimal inhibitory concentration,, ug/ml, dissolved in IV, IV-dimethylacetamide (ref
4).'Norwich Pharmacal culture num-ber.“Potency= 4162 units/mg. hr. The resultantbright …