[PDF][PDF] Agent optimization: absorption, distribution, metabolism, excretion, dose, and decay

MW Brechbiel - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Targeted radiation therapy (TRT) is undergoing another renaissance attributable to US Food
and Drug Administration approvals of 223RaCl2 (Xofigo; Bayer) and 177Lu-DOTATATE …

[HTML][HTML] From fixed activities to personalized treatments in radionuclide therapy: lost in translation?

GD Flux, K Sjogreen Gleisner, C Chiesa… - European Journal of …, 2018 - Springer
We read with interest the letter by Giammarile et al.[1] addressing our editorial in which we
proposed that the European Medicines Agency should allow the option of a dosimetrybased …

Proceedings of the Second NCI–SNMMI workshop on targeted radionuclide therapy

F Fahey, K Zukotynski, H Jadvar… - Journal of Nuclear …, 2015 - Soc Nuclear Med
In 2013, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the National
Cancer Institute (NCI) partnered for the first time to host a joint workshop on targeted …

[PDF][PDF] Radiopharmaceutical dosimetry for cancer therapy: From theory to practice

RL Wahl, J Sunderland - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
This supplement to The Journal of Nuclear Medicine includes 7 articles that address several
of the critical facets of the current state of radiation dosimetry in radiopharmaceutical …

[HTML][HTML] The conflict between treatment optimization and registration of radiopharmaceuticals with fixed activity posology in oncological nuclear medicine therapy

C Chiesa, K Sjogreen Gleisner, G Flux, J Gear… - European Journal of …, 2017 - Springer
(Optimisation) states: BFor all medical exposure of patients for radiotherapeutic purposes,
exposures of target volumes shall be individually planned and their delivery appropriately …

[PDF][PDF] A Bridge not too Far: Personalized Medicine with the use of Theragnostic Radiopharmaceuticals

SC Srivastava - J. Postgrad. Med. Educ. Res, 2013 - prrtinfo.org
This article deals primarily with the selection criteria, production, and the nuclear, physical,
and chemical properties of certain dual-purpose radionuclides, including those that are …

Creating the platform for next-generation radiopharmaceuticals

A Shomir - nature.com
Radiopharmaceuticals play a key role in medicine. In addition to being a diagnostic tool,
they are also used therapeutically in the treatment of cancer; radioactive iodine-131 has …

Therapeutic radionuclides: production, physical characteristics, and applications

SC Srivastava, LF Mausner - Therapeutic nuclear medicine, 2013 - Springer
This chapter will focus primarily on the selection criteria, production, and the nuclear,
physical, and chemical properties of therapeutic radionuclides, including those that are …

[HTML][HTML] Radionuclides for targeted therapy: physical properties

C Stokke, M Kvassheim, J Blakkisrud - Molecules, 2022 - mdpi.com
A search in PubMed revealed that 72 radionuclides have been considered for molecular or
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …

Dosimetry for radiopharmaceutical therapy

G Sgouros, RF Hobbs - Seminars in nuclear medicine, 2014 - Elsevier
Radiopharmaceutical therapy (RPT) involves the use of radionuclides that are either
conjugated to tumor-targeting agents (eg, nanoscale constructs, antibodies, peptides, and …