Today, PET and SPECT tracers cannot be imaged simultaneously at high resolutions but
require 2 separate imaging systems. This paper introduces a Versatile Emission Computed …

A major advance in biomedical science and diagnosis was accomplished with the
development of in vivo techniques to image radiolabeled molecules, but limited spatial …

Recently, we launched a stationary SPECT system (U-SPECT-I) dedicated to small-animal
imaging. A cylinder with 75 gold micropinhole apertures that focus on a mouse organ was …

Molecular imaging of small animals in vivo is vital in the study of mouse and rat models of
human diseases, and will provide important clues to the pathogenesis, progression and …

State-of-the-art small-animal single photon emission computed tomography (SPECT)
enables sub-half-mm resolution imaging of radio-labelled molecules. Due to severe photon …

SPECT with submegabecquerel amounts of tracer or subsecond time resolution would
enable a wide range of new imaging protocols such as screening tracers with initially low …

Limited spatial resolution of preclinical positron emission tomography (PET) and single-
photon emission computed tomography (SPECT) has slowed down applications of …

Preclinical SPECT of rodents is both in demand and very demanding. The need for high
spatial resolution in combination with good sensitivity has given rise to considerable …

Multi-pinhole (MPH) collimators are known to provide better trade-off between sensitivity and
resolution for preclinical, as well as for smaller regions in clinical SPECT imaging compared …

The need to study dynamic biologic processes in intact small-animal models of disease has
stimulated the development of high-resolution nuclear imaging methods. These methods are …