The role of amyloid PET in imaging neurodegenerative disorders: a review

M Chapleau, L Iaccarino… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Imaging of amyloid deposition using PET has been available in research studies for 2
decades and has been approved for clinical use by the US Food and Drug Administration …

Clinical amyloid imaging

A Mallik, A Drzezga, S Minoshima - Seminars in nuclear medicine, 2017 - Elsevier
Amyloid plaques, along with neurofibrillary tangles, are a neuropathologic hallmark of
Alzheimer disease (AD). Recently, amyloid PET radiotracers have been developed and …

[HTML][HTML] Amyloid PET imaging: applications beyond Alzheimer's disease

AM Catafau, S Bullich - Clinical and translational imaging, 2015 - Springer
As a biomarker of beta-amyloid, positron emission tomography (PET) amyloid imaging offers
a unique opportunity to detect the presence of this protein in the human body during life …

Should we disclose amyloid imaging results to cognitively normal individuals?

JD Grill, DK Johnson, JM Burns - Neurodegenerative Disease …, 2013 - Future Medicine
Demonstration of brain accumulation of fibrillar amyloid-β protein via PET with amyloid-
specific ligands may support the diagnosis of Alzheimer's disease (AD). There is increasing …

Amyloid PET imaging in clinical practice

MA Kolanko, Z Win, F Loreto, N Patel, C Carswell… - Practical …, 2020 - pn.bmj.com
Amyloid positron emission tomography (PET) imaging enables in vivo detection of brain Aβ
deposition, one of the neuropathological hallmarks of Alzheimer's disease. There is …

[HTML][HTML] Quantification of amyloid PET for future clinical use: a state-of-the-art review

HG Pemberton, LE Collij, F Heeman, A Bollack… - European journal of …, 2022 - Springer
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …

[HTML][HTML] Amyloid-β imaging with PET in Alzheimer's disease: is it feasible with current radiotracers and technologies?

MC Moghbel, B Saboury, S Basu, SD Metzler… - European journal of …, 2012 - Springer
Although it afflicts an estimated 26.6 million people worldwide—a figure that is expected to
quadruple by 2050—Alzheimer's disease (AD) has yet to be fully understood etiologically …

Cerebral amyloid PET imaging in Alzheimer's disease

CR Jack, JR Barrio, V Kepe - Acta neuropathologica, 2013 - Springer
The devastating effects of the still incurable Alzheimer's disease (AD) project an ever
increasing shadow of burden on the health care system and society in general. In this …

Clinical use and utility of amyloid imaging

H Barthel, O Sabri - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
Currently, 3 amyloid PET tracers are approved and commercially available for clinical use.
They allow for the accurate in vivo detection of amyloid plaques, one hallmark of Alzheimer …

Brain amyloid imaging

CC Rowe, VL Villemagne - Journal of nuclear medicine …, 2013 - Soc Nuclear Med
Imaging of brain β-amyloid plaques with 18F-labeled tracers for PET will likely be available
in clinical practice to assist the diagnosis of Alzheimer disease (AD). With the rapidly …