Imaging inflammation in atherosclerosis with CXCR4-directed 68Ga-pentixafor PET/CT: correlation with 18F-FDG PET/CT

M Kircher, J Tran-Gia, L Kemmer, X Zhang… - Journal of Nuclear …, 2020 - Soc Nuclear Med
CXC motif chemokine receptor 4 (CXCR4) is expressed on the surface of various cell types
involved in atherosclerosis, with a particularly rich receptor expression on macrophages and …

Imaging the cytokine receptor CXCR4 in atherosclerotic plaques with the radiotracer 68Ga-pentixafor for PET

F Hyafil, J Pelisek, I Laitinen, M Schottelius… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68Ga-pentixafor is a radiotracer for PET that binds with nanomolar affinity to CXCR4. The
CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study …

Clinical molecular imaging of chemokine receptor CXCR4 expression in atherosclerotic plaque using 68Ga-pentixafor PET: correlation with cardiovascular risk factors …

D Weiberg, JT Thackeray, G Daum… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The CXC-motif chemokine receptor 4 (CXCR4) represents a promising target for molecular
imaging of different CXCR4-positive cell types in cardiovascular diseases such as …

[HTML][HTML] [68Ga] Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques

X Li, D Heber, T Leike, D Beitzke, X Lu, X Zhang… - European Journal of …, 2018 - Springer
Purpose The expression of chemokine receptor type 4 (CXCR4) was found co-localized with
macrophages on the atherosclerotic vessel wall and participated in the initial emigration of …

[HTML][HTML] [68Ga]Pentixafor PET/MR imaging of chemokine receptor 4 expression in the human carotid artery

X Li, W Yu, T Wollenweber, X Lu, Y Wei… - European Journal of …, 2019 - Springer
Purpose Type 4 chemokine receptor (CXCR4) plays an important role in immune cell
migration during the atherosclerosis progression. We aimed to evaluate [68 Ga] Pentixafor …

[HTML][HTML] Imaging of chemokine receptor CXCR4 expression in culprit and nonculprit coronary atherosclerotic plaque using motion-corrected [68Ga]pentixafor PET/CT

T Derlin, DG Sedding, J Dutzmann, A Haghikia… - European journal of …, 2018 - Springer
Purpose The chemokine receptor CXCR4 is a promising target for molecular imaging of
CXCR4+ cell types, eg inflammatory cells, in cardiovascular diseases. We speculated that a …

Atherosclerosis inflammation imaging with 18F-FDG PET: carotid, iliac, and femoral uptake reproducibility, quantification methods, and recommendations

JHF Rudd, KS Myers, S Bansilal… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Atherosclerosis imaging with 18F-FDG PET is useful for tracking inflammation within plaque
and monitoring the response to drug therapy. Short-term reproducibility of this technique in …

CXCR4-binding positron emission tomography tracers link monocyte recruitment and endothelial injury in murine atherosclerosis

O Baba, LH Huang, A Elvington… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: vMIP-II (viral macrophage inflammatory protein 2)/vCCL2 (viral chemotactic
cytokine ligand 2) binds to multiple chemokine receptors, and vMIP-II-based positron …

[HTML][HTML] Imaging of CXC Motif Chemokine Receptor CXCR4 Expression After Myocardial Infarction With [68Ga]Pentixafor-PET/CT in Correlation With Cardiac MRI

T Reiter, M Kircher, A Schirbel, RA Werner… - JACC: Cardiovascular …, 2018 - jacc.org
CXC motif chemokine receptor 4 (CXCR4) and its ligand stromal cell-derived factor-1a have
been shown to be involved in the orchestration of postinfarct inflammation and its resolution …

Delayed 18F-fluorodeoxyglucose PET/CT imaging improves quantitation of atherosclerotic plaque inflammation: results from the CAMONA study

BA Blomberg, A Thomassen, RAP Takx… - Journal of Nuclear …, 2014 - Elsevier
Background This study aimed to determine if delayed 18 F-fluorodeoxyglucose (18 FDG)
PET/CT imaging improves quantitation of atherosclerotic plaque inflammation. Blood-pool …