[PDF][PDF] Regression of advanced refractory ovarian cancer treated with iodine-131-labeled anti-CEA monoclonal antibody

M Juweid, RM Sharkey, A Alavi… - Journal of Nuclear …, 1997 - Soc Nuclear Med
Advanced chemotherapy-resistant ovarian cancer has a poor prog nosis, thus requiring new
therapeutic modalities. Acomplete clinical remission, using two cycles of 131l-labeled …

Prospects of radioimmunotherapy in epithelial ovarian cancer: results with iodine-131-labeled murine and humanized MN-14 anti-carcinoembryonic antigen …

M Juweid, LC Swayne, RM Sharkey, R Dunn… - Gynecologic …, 1997 - Elsevier
Objectives. Epithelial ovarian cancer (EOC) is known to produce carcinoembryonic antigen
(CEA), and the plasma CEA level is frequently elevated in patients with advanced stage and …

Use of indium-111-labeled OC-125 monoclonal antibody in the detection of ovarian cancer

RE Hunter, P Doherty, TW Griffin, M Gionet… - Gynecologic …, 1987 - Elsevier
This is a preliminary study to evaluate the utility of using the monoclonal antibody (CO-125)
labeled with indium-111 to image recurrences of ovarian cancer. This technique has been …

Immunoscintigraphy using CA 125 antibodies in the management of ovarian cancer

J Brökelmann, A Bockisch, J Vogel, J Reinsberg… - Archives of Gynecology …, 1989 - Springer
Radioimmundetection (RID) using anti-CA 125 antibodies proved to be a valuable tool in the
follow-up of metastasizing ovarian cancer. Sensitivity, specificity, and accuracy were high …

Usefulness of imaging ovarian cancer recurrence with In-111-labeled monoclonal antibody (OC125) specific for CA125 antigen

P Peltier, JP Dutin, JF Chatal, P Fumoleau… - Annals of oncology, 1993 - Elsevier
Background A progressive rise in serum CA 125 concentration during follow-up monitoring
of ovarian cancer after treatment of primary tumor is suggestive of a recurrence. Patients and …

Addition of cisplatin improves efficacy of 131I-labeled monoclonal antibody 323A3 in experimental human ovarian cancer

E Kievit, HM Pinedo, HMM Schlüper, E Boven - International Journal of …, 1997 - Elsevier
Purpose: This study was conducted to determine whether the cytotoxic agent cisplatin
(CDDP), also known as a radiosensitizer, can improve the efficacy of the 131I-labeled …

Radioimmunoscintigraphy using monoclonal antibodies to CEA, CA 19-9 and CA 125

RP Baum, M Lorenz, C Hottenrott… - The International …, 1988 - journals.sagepub.com
131I labelled F (ab') 2 fragments of monoclonal antibodies against CA 19-9 and CEA
(“radioimmunococktail” IMACIS 1) were used in a prospective study (n= 60 patients) and in a …

Effect of circulating antigen on immunoscintigraphy of ovarian cancer patients using anti‐CA125 monoclonal antibody

H Sakahara, M Hosono, H Kobayashi… - Japanese journal of …, 1996 - Wiley Online Library
The murine monoclonal antibody (mAb) 145–9 recognizes an epitope present on CA125 but
different from the epitope defined by the mAb OC125. To evaluate the clinical usefulness of …

[PDF][PDF] Anti-chelate antibodies after intraperitoneal yttrium-90-labeled monoclonal antibody immunoconjugates for ovarian cancer therapy

C Kosmas, A Maraveyas, CS Gooden… - Journal of Nuclear …, 1995 - Soc Nuclear Med
MATERIALSAND METhODS Padents Twelve patients with epitheial ovarian cancer
participated in a Phase I/il clinical trial of intraperitoneal administration of@ ÂY HMFG1-CITC …

A human/mouse chimeric monoclonal antibody against CA125 for radioimmunoimaging of ovarian cancer

H Kobavashi, H Sakahara, T Saga, M Hosono… - Cancer Immunology …, 1993 - Springer
Murine monoclonal antibody 196-14 recognizes the ovarian-cancer-associated antigen CA
125, but the epitope it recognizes is different from that of monoclonal antibody OC125. We …