99mTc-Mercaptoacetyltriglycine (99mTc-MAG3), 99mTc-dd-and ll-ethylene-dicysteine
(99mTc-EC), and 99mTc-mercaptoacetamide-ethylene-cysteine (99mTc-MAEC) contain …

INTRODUCTION: The first human studies of a characterized radiopharmaceutical containing
a {99mTc (CO) 3}+ core, Na [99mTc (CO) 3 (LAN)], demonstrated that Na [99mTc (CO) 3 …

Studies in rats showed that the pharmacokinetics of the tricarbonyl core radiopharmaceutical
99mTc (CO) 3-nitrilotriacetic acid, 99mTc (CO) 3 (NTA), were essentially identical to those of …

The pharmacokinetics of the tricarbonyl core radiopharmaceutical 99mTc (CO) 3-
nitrilotriacetic acid (99mTc (CO) 3 (NTA)) in rats and subjects with normal renal function are …

Abstract Introduction 99m Tc (CO) 3-nitrilotriacetic acid, 99m Tc (CO) 3 (NTA), is a new renal
tubular agent with pharmacokinetic properties comparable to those of 131 I-OIH but the …

To develop a 99mTc renal tracer with a capacity to measure effective renal plasma flow
comparable to that of the clinical gold standard 131I-o-iodohippurate (131I-OIH) and …

99mTc-Mercaptoacetyltriglycine (99mTc-MAG3) and 99mTc-l, l-ethylenedicysteine (99mTc-ll-
EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances …

The coordination chemistry of lanthionine (LANH2) and cystathionine (CSTH2) dipeptides,
which respectively consist of two cysteines and one cysteine and one homocysteine linked …

A number of diamide dimercaptide (N/sub 2/S/sub 2/) complexes of Tc-99m have shown
potential as renal tubular function radiopharmaceuticals that could replace radioiodinated …

Technetium-99m mercaptoacetylglycylglycylglycine (MAG3), a [99mTc] triamide mercaptide
(N3S) compound has been synthesized in an attempt to obviate the stereochemistry …