[PDF][PDF] Imaging inflammatory diseases with neutrophil-specific technetium-99m-labeled monoclonal antibody anti-SSEA-1

ML Thakur, CS Marcus, P Henneman… - Journal of Nuclear …, 1996 - Soc Nuclear Med
±3.2% administered dose, liver uptake was at the upper limit with 111ln-WBC uptake.
Renal uptake was only 2.4% ±0.03% admin istered dose. At 2 hr postinjection, 14% to 51 …

Intraindividual comparison of 99mTc-labelled anti-SSEA-1 antigranulocyte antibody and 99mTc-HMPAO labelled white blood cells for the imaging of infection

S Gratz, T Behr, A Herrmann, K Dresing… - European journal of …, 1998 - Springer
Technetium-99m labelled antigranulocyte antibodies are ready to use and are sensitive and
specific in the diagnosis of infectious diseases. 99m Tc-SSEA antigranulocyte antibodies …

Mechanism of accumulation of 99mTc-sulesomab in inflammation

SJ Skehan, JF White, JW Evans… - Journal of Nuclear …, 2003 - Soc Nuclear Med
99mTc-Sulesomab, the Fab fragment of anti-NCA-90, is used as an in vivo granulocyte
labeling agent for imaging inflammation. It is not clear to what extent it targets cells that have …

Scintigraphic detection of TNF-driven inflammation by radiolabelled certolizumab pegol in patients with rheumatoid arthritis and spondyloarthritis

P Carron, B Lambert, L Van Praet, F De Vos… - RMD open, 2016 - rmdopen.bmj.com
Background Biologicals are the cornerstone for many treatment algorithms in inflammatory
arthritis. While tumour necrosis factor (TNF) inhibitors may achieve important responses in∼ …

Functional imaging of inflammatory diseases using nuclear medicine techniques

S Basu, H Zhuang, DA Torigian, J Rosenbaum… - Seminars in nuclear …, 2009 - Elsevier
Molecular imaging with positron emission tomography (PET) and single-photon emission
computed tomography (SPECT) is increasingly used to diagnose, characterize, and monitor …

Imaging rheumatic joint diseases with anti-T lymphocyte antibody OKT-3

C Marcus, ML Thakur, TV Huynh, JS Louie… - Nuclear medicine …, 1994 - journals.lww.com
T lymphocytes play an important role in the pathogenesis of rheumatoid arthritis (RA).
Murine monoclonal antibody OKT-3 (IgG2a), known to be specific for T lymphocyte 20 kD …

[PDF][PDF] Targeting NCA-95 and other granulocyte antigens and receptors with radiolabeled monoclonal antibodies (Mabs)

J Meller, T Liersch, MM Oezerden… - Quarterly Journal of …, 2010 - researchgate.net
During the last decade considerable effort has been made in the research for in vivo
techniques of labeling neutrophils with peptides, labeled cytokines and 99mTc-labeled …

Scintigraphic imaging of inflammatory processes

HJJM Rennen, OC Boerman, WJG Oyen… - Medicinal Chemistry …, 2004 - ingentaconnect.com
Nuclear medicine offers ideal techniques to visualize inflammatory processes using
noninvasive methods of whole-body scanning, enabling the determination of both the …

A novel model for the pre-clinical imaging of inflamed human synovial vasculature

T Garrood, M Blades, DO Haskard, S Mather… - …, 2009 - academic.oup.com
Objective. The purpose of this study was to explore the development of a pre-clinical nuclear
imaging model as a tool for testing novel radiopharmaceutical agents for imaging and/or …

Radioimmunotherapy of non-Hodgkin's lymphoma revisited

DM Goldenberg, RM Sharkey - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
TO THE EDITOR: I congratulate Skehan et al.(1) on their recent study on the mechanism by
which 99mTc-sulesomab (Leuko-Scan; Immunomedics, Inc.) accumulates in inflammation …