18F-FDG kinetics and gene expression in giant cell tumors

LG Strauss, A Dimitrakopoulou-Strauss… - Journal of Nuclear …, 2004 - Soc Nuclear Med
18F-FDG kinetics were evaluated by use of compartment and noncompartment models of
giant cell tumors. The kinetic data were compared with the gene expression data for a …

Impact of angiogenesis-related gene expression on the tracer kinetics of 18F-FDG in colorectal tumors

LG Strauss, D Koczan, S Klippel, L Pan… - Journal of Nuclear …, 2008 - Soc Nuclear Med
18F-FDG kinetics are primarily dependent on the expression of genes associated with
glucose transporters and hexokinases but may be modulated by other genes. The …

Characterization of 18F-FDG uptake in human endothelial cells in vitro

S Maschauer, O Prante, M Hoffmann… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The contribution of 18F-FDG uptake by endothelial cells to uptake values measured by PET
in various tissues is as yet unclear. We therefore sought to characterize 18F-FDG uptake in …

Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors

K Kaira, T Okumura, Y Ohde, T Takahashi… - Journal of Nuclear …, 2011 - Soc Nuclear Med
18F-FDG PET can help in predicting therapeutic response and outcome in patients with
metastatic pulmonary tumors. However, no satisfactory biologic explanation exists for this …

Dynamic PET 18F-FDG studies in patients with primary and recurrent soft-tissue sarcomas: impact on diagnosis and correlation with grading

A Dimitrakopoulou-Strauss, LG Strauss… - Journal of Nuclear …, 2001 - Soc Nuclear Med
The purpose of this study was to evaluate 18F-FDG PET studies of primary and recurrent
sarcomas for diagnosis and correlation with grading. Methods: The evaluation included 56 …

Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG

AK Buck, G Halter, H Schirrmeister… - Journal of nuclear …, 2003 - Soc Nuclear Med
Recently, the thymidine analog 3′-deoxy-3′-18F-fluorothymidine (FLT) was suggested for
imaging tumoral proliferation. In this prospective study, we examined whether 18F-FLT …

The role of quantitative 18F-FDG PET studies for the differentiation of malignant and benign bone lesions

A Dimitrakopoulou-Strauss, LG Strauss… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The role of quantitative 18F-FDG PET studies for the differentiation of benign and malignant
bone lesions is still an open question. Methods: Our evaluation included 83 patients with 37 …

Preclinical dynamic 18F-FDG PET – tumor characterization and radiotherapy response assessment by kinetic compartment analysis

K Røe, TB Aleksandersen, A Kristian, LB Nilsen… - Acta …, 2010 - Taylor & Francis
Background. Non-invasive visualization of tumor biological and molecular processes of
importance to diagnosis and treatment response is likely to be critical in individualized …

18F-FDOPA kinetics in brain tumors

C Schiepers, W Chen, T Cloughesy… - Journal of Nuclear …, 2007 - Soc Nuclear Med
l-3, 4-Dihydroxy-6-18F-fluoro-phenyl-alanine (18F-FDOPA) is an amino acid analog used to
evaluate presynaptic dopaminergic neuronal function. Evaluation of tumor recurrence in …

The role of 18F-FLT in cancer imaging: does it really reflect proliferation?

A Dimitrakopoulou-Strauss, LG Strauss - European journal of nuclear …, 2008 - Springer
Proliferating cells synthesize DNA during the S phase of the cell cycle. The pyrimidine
analogue thymidine is the only nucleoside that is exclusively incorporated into DNA but not …