18F-Flumazenil: A γ-aminobutyric acid A–Specific PET radiotracer for the localization of drug-resistant temporal lobe epilepsy
L Vivash, MC Gregoire, EW Lau, RE Ware… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Studies report that 11C-flumazenil (FMZ) PET more specifically localizes the epileptogenic
zone in patients with medically refractory focal epilepsy than 18F-FDG PET. However …
zone in patients with medically refractory focal epilepsy than 18F-FDG PET. However …
11C-flumazenil PET in patients with refractory temporal lobe epilepsy and normal MRI
Background: Using 11C-flumazenil (FMZ) PET with correction for partial-volume effect,
reductions of central benzodiazepine receptor (cBZR) binding can be detected reliably in …
reductions of central benzodiazepine receptor (cBZR) binding can be detected reliably in …
[HTML][HTML] Clinical utility of 11C-flumazenil positron emission tomography in intractable temporal lobe epilepsy
MV Padma, R Simkins, P White, M Satter… - Neurology …, 2004 - journals.lww.com
BACKGROUND: 11C-flumazenil (FMZ) positron emission tomography (PET) is a new
entrant into the armamentarium for pre-surgical evaluation of patients with intractable …
entrant into the armamentarium for pre-surgical evaluation of patients with intractable …
[11C]Flumazenil PET in Temporal Lobe Epilepsy: Do We Need an Arterial Input Function or Kinetic Modeling?
A Hammers, P Panagoda… - Journal of Cerebral …, 2008 - journals.sagepub.com
Reduced signal on [11C]] flumazenil (FMZ) positron emission tomography (PET) is
associated with epileptogenic foci. Linear correlations within individuals between parametric …
associated with epileptogenic foci. Linear correlations within individuals between parametric …
MRI-guided flumazenil-and FDG-PET in temporal lobe epilepsy
B Szelies, G Weber-Luxenburger, G Pawlik, J Kessler… - Neuroimage, 1996 - Elsevier
In temporal lobe epilepsy (TLE) patients without lesions, major hippocampal sclerosis, or
atrophy on magnetic resonance imaging (MRI), the localizing power of [11C] flumazenil …
atrophy on magnetic resonance imaging (MRI), the localizing power of [11C] flumazenil …
18F‐FCWAY and 18F‐FDG PET in MRI‐negative temporal lobe epilepsy
CJ Liew, YM Lim, R Bonwetsch, S Shamim, S Sato… - …, 2009 - Wiley Online Library
Background: Positron emission tomography (PET) with 18F‐fluorodeoxyglucose (FDG)
shows widespread hypometabolism even in temporal lobe epilepsy (TLE) patients with …
shows widespread hypometabolism even in temporal lobe epilepsy (TLE) patients with …
[11C]Flumazenil binding in the medial temporal lobe in patients with temporal lobe epilepsy: Correlation with hippocampal MR volumetry, T2 relaxometry, and …
S Lamusuo, A Pitkanen, L Jutila, A Ylinen, K Partanen… - Neurology, 2000 - AAN Enterprises
Objective: To detect reduced [11C] flumazenil in patients with temporal lobe epilepsy (TLE)
and to relate binding to histopathology. Methods: The authors studied 16 patients who …
and to relate binding to histopathology. Methods: The authors studied 16 patients who …
[HTML][HTML] Combined quantitative T2 mapping and [18F]FDG PET could improve lateralization of mesial temporal lobe epilepsy
M Zhang, H Huang, W Liu, L Tang, Q Li, J Wang… - European …, 2022 - Springer
Objectives To investigate whether quantitative T2 mapping is complementary to [18F] FDG
PET in epileptogenic zone detection, thus improving the lateralization accuracy for drug …
PET in epileptogenic zone detection, thus improving the lateralization accuracy for drug …
Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI
In 20% of potential surgical candidates with refractory epilepsy, current optimal MRI does not
identify the cause. GABA is the principal inhibitory neurotransmitter in the brain, and GABAA …
identify the cause. GABA is the principal inhibitory neurotransmitter in the brain, and GABAA …
[11ClFlumazenil PET in Patients with Epilepsy with Dual Pathology
C Juhász, F Nagy, O Muzik, C Watson, J Shah… - …, 1999 - Wiley Online Library
Purpose: Coexistence of hippocampal sclerosis and a potentially epileptogenic cortical
lesion is referred to as dual pathology and can be responsible for poor surgical outcome in …
lesion is referred to as dual pathology and can be responsible for poor surgical outcome in …
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